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首页> 外文期刊>Archives of Biological Sciences >DIRECT CORRELATION BETWEEN THE SCORES OF PANSS/AIMS SCALES AND SOME OXIDATIVE STRESS MARKERS IN TREATED SCHIZOPHRENIC PATIENTS
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DIRECT CORRELATION BETWEEN THE SCORES OF PANSS/AIMS SCALES AND SOME OXIDATIVE STRESS MARKERS IN TREATED SCHIZOPHRENIC PATIENTS

机译：治疗型精神分裂症患者的PANSS / AIMS评分与某些氧化应激标记之间的直接相关性

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Oxidative stress is increasingly viewed as potentially important in the pathophysiology of schizophrenia, although most results regarding this subject are contradictory. We previously demonstrated an increased oxidative stress status in schizophrenic patients, regardless of their treatment. In this paper, we were interested in whether there is a correlation between the specific activities of the most important antioxidant enzymes (superoxide dismutase and glutathione peroxidase) and a lipid peroxidation marker (malondialdehyde) and the scores of PANSS/AIMS scales. A direct significant correlation was observed between oxidative stress markers and the aforementioned scales. Our results provide additional evidence regarding the implications of oxidative stress in patients with schizophrenia.
机译：氧化应激越来越多地被认为在精神分裂症的病理生理中具有潜在的重要性，尽管有关该主题的大多数结果是矛盾的。先前我们证明了精神分裂症患者的氧化应激状态增加，无论其治疗如何。在本文中，我们感兴趣的是最重要的抗氧化酶（超氧化物歧化酶和谷胱甘肽过氧化物酶）和脂质过氧化标志物（丙二醛）的比活与PANSS / AIMS评分之间是否存在相关性。在氧化应激标志物和上述量表之间观察到直接显着的相关性。我们的结果提供了关于精神分裂症患者氧化应激影响的其他证据。

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