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Relationship between blood plasma IGF-1 and GH concentrations and growth of Holstein steers

机译:血浆IGF-1和GH浓度与荷斯坦ste牛生长的关系

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Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) have been studied as indicators of growth potential in beef cattle, but these relationships had not been studied previously in Holstein steers. In this case 12 calves weaned at a mean age of 45 d and body weight (BW) of 54.6 kg were used to obtain, every 28 d during a 336-day experiment, BW data and blood samples. Ten blood samples collected at 30-minute intervals, from 0800 to 1300 h were mixed together and analyzed for concentration of IGF-1 and GH by radio-immuno assay. Linear regression and correlation analyses were performed to determine the relationship between average daily gain (ADG) and BW, and plasma IGF-1 and GH concentrations. The correlations between plasma IGF-1 and ADG or BW were consistently positive (0.47 and 0.48), but those between GH and ADG or BW were negative (-0.31 and - 0.37, respectively). Plasma concentration of IGF-1 explained 24% of the variation in ADG, but GH explained only about 10%. Concentration of IGF-1 showed a strong relationship with BW (R2 = 0.41) throughout a 336-day period of growth. These data indicate that plasma IGF-1 may be useful for predicting performance of Holstein steers.
机译:已经研究了胰岛素样生长因子-1(IGF-1)和生长激素(GH)作为肉牛生长潜力的指标,但是以前在荷斯坦牛中没有研究过这些关系。在这种情况下,在336天的实验中每28 d用12头平均年龄为45 d断奶的犊牛和54.6 kg的体重(BW)获得体重数据和血液样本。在30分钟的间隔(从0800到1300小时)收集的十份血液样本混合在一起,并通过放射免疫分析法分析了IGF-1和GH的浓度。进行线性回归和相关分析,以确定平均日增重(ADG)和体重以及血浆IGF-1和GH浓度之间的关系。血浆IGF-1与ADG或BW之间的相关性始终为正(0.47和0.48),而GH与ADG或BW之间的相关性为负(分别为-0.31和-0.37)。 IGF-1的血浆浓度解释了ADG变异的24%,而GH仅解释了约10%。在生长的336天中,IGF-1的浓度与BW密切相关(R 2 = 0.41)。这些数据表明血浆IGF-1可能对预测荷斯坦stein牛的性能有用。

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