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首页> 外文期刊>Annals of Indian Academy of Neurology >Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India
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Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India

机译：轻度认知障碍的神经心理学标记：来自印度城市的一项基于临床的研究

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Background: Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia. Persons with MCI are at higher risk to develop dementia. Identifying MCI from normal aging has become a priority area of research. Neuropsychological assessment could help to identify these high risk individuals. Objective: To examine clinical utility and diagnostic accuracy of neuropsychological measures in identifying MCI. Materials and Methods: This is a cross-sectional study of 42 participants (22 patients with MCI and 20 normal controls [NC]) between the age of 60 and 80 years. All participants were screened for dementia and later a detailed neuropsychological assessment was carried out. Results: Persons with MCI performed significantly poorer than NC on word list (immediate and delayed recall), story recall test, stick construction delayed recall, fluency and Go/No-Go test. Measures of episodic memory especially word list delayed recall had the highest discriminating power compared with measures of semantic memory and executive functioning. Conclusion: Word list learning with delayed recall component is a possible candidate for detecting MCI from normal aging.
机译：背景：轻度认知障碍（MCI）是正常衰老和痴呆症之间的过渡阶段。 MCI患者罹患痴呆症的风险更高。从正常老化中识别MCI已成为研究的优先领域。神经心理学评估可以帮助识别这些高危人群。目的：探讨神经心理学方法在鉴别MCI中的临床实用性和诊断准确性。材料和方法：这是一项对60位至80岁之间的42位参与者（22位MCI患者和20位正常对照[NC]）进行的横断面研究。筛选所有参与者的痴呆症，然后进行详细的神经心理学评估。结果：MCI患者在单词列表（立即回忆和延迟回忆），故事回忆测试，棍子构造延迟回忆，流利性和通过/不通过测试方面的表现明显不如NC。与语义记忆和执行功能相比，情景记忆尤其是单词表延迟回忆的测量具有最高的辨别力。结论：具有延迟回忆成分的单词列表学习是从正常衰老中检测MCI的可能候选者。

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