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首页> 外文期刊>Asian spine journal. >The Spectrum of Clinical and Urodynamic Findings in Patients with Spinal Tuberculosis Exhibiting Lower Urinary Tract Symptoms, before and after Spinal Surgical Intervention with Antitubercular Treatment: A Prospective Study
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The Spectrum of Clinical and Urodynamic Findings in Patients with Spinal Tuberculosis Exhibiting Lower Urinary Tract Symptoms, before and after Spinal Surgical Intervention with Antitubercular Treatment: A Prospective Study

机译：脊髓外科手术抗结核治疗前后表现为下尿路症状的脊柱结核患者的临床和尿动力学检查结果的范围：一项前瞻性研究

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Study Design Observational study. Purpose This study aims to assess the clinical and urodynamic parameters in patients with spinal tuberculosis (TB) exhibiting lower urinary tract symptoms (LUTS) at the time of presentation and after spinal surgical intervention. Overview of Literature Variable urodynamic findings in patients with spinal TB. Methods We prospectively evaluated 10 patients with spinal TB exhibiting LUTS. Urinary symptoms were assessed by the American Urological Association (AUA) symptom score. We performed a urodynamic study (UDS), including electromyography, in all patients before and 3 months after spinal surgery. Results The mean age of patients was 29.7 years (range, 15–52 years), and the mean AUA symptom score was 12.5 and 11.8 before and after spinal surgery, respectively. Overall, five patients exhibited improvement in the AUA symptom score, and three showed no change, while two patients’ condition worsened. We observed detrusor overactivity (DO) in two patients, and detrusor sphincter dyssynergia (DSD) in four patients. In addition, high-pressure voiding (HPV) was noted in two patients. On follow-up after spinal surgery, DO and DSD exhibited no improvement. Although HPV resolved, two patients developed new-onset poor compliance with worsening DO and DSD. Furthermore, two patients had bilateral hydronephrosis before surgery, which resolved on follow-up. Conclusions Patients with spinal TB exhibiting LUTS can display a spectrum of clinical presentations and variable UDS findings. As two patients exhibited new onset poor compliance with bilateral hydronephrosis in one of them, this study concludes that a close follow-up for upper tracts in these patients is required despite successful spinal surgery.
机译：研究设计观察性研究。目的本研究旨在评估在就诊时以及在进行脊柱外科手术后表现出下尿路症状（LUTS）的脊柱结核（TB）患者的临床和尿动力学参数。文献综述脊柱结核患者的尿动力学检查结果可变。方法我们前瞻性评估了10例表现出LUTS的脊柱结核患者。泌尿系统症状通过美国泌尿科协会（AUA）症状评分进行评估。我们对所有脊柱手术前后的患者进行了尿动力学研究（UDS），包括肌电图检查。结果患者的平均年龄为29.7岁（范围15-52岁），脊柱手术前后平均AUA症状评分分别为12.5和11.8。总体而言，有5例患者的AUA症状评分有所改善，有3例患者无变化，而2例患者的病情恶化。我们观察到两名患者逼尿肌过度活动（DO），和四名患者逼尿肌括约肌功能障碍（DSD）。另外，在两名患者中发现了高压排尿（HPV）。脊柱手术后的随访中，DO和DSD均无改善。尽管HPV消退，但两名患者因DO和DSD恶化而出现新发依从性差。此外，有2例患者术前双侧肾积水，经随访后消失。结论表现出LUTS的脊柱结核患者可以显示一系列临床表现和可变的UDS结果。由于其中两名患者在其中一名患者中出现新发的对双侧肾积水的依从性较差，因此该研究得出结论，尽管脊柱手术成功，但仍需要对这些患者的上呼吸道进行密切随访。

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