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Perineuronal net aberrations as a putative mechanism of behavioral and neural alterations in DISC-1 mutation model of schizophrenia

机译:神经氨酸净异常是精神分裂症 DISC-1 突变模型中行为和神经变化的推测机制

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Here, we report a new canine model of drug-induced RD with sodium iodate (SI) injection after vitrectomy. Conclusion: In histology, 1.2 mg of SI induced the localized RD only in outer not in inner retina of canine model. In future study, we would like to optimize SI dose to establish RD canine model which might be applied to a preclinical study for developing the retinal prosthesis.
机译:在这里,我们报告玻璃体切除术后注射碘酒(SI)注射药物引起的RD的新犬科动物模型。结论:在组织学中,1.2 mg SI诱导仅在犬模型的外部而非内部视网膜中引起局部RD。在未来的研究中,我们希望优化SI剂量以建立RD犬模型,该模型可用于开发视网膜假体的临床前研究。

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