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Aspectos imaginológicos del sarcoma granulocítico en la cara y el cráneo de ni?os y jóvenes: informe de cinco casos y revisión de la literatura

机译:儿童和年轻人的面部和颅骨中的粒细胞肉瘤的影像学表现:五例报告并文献复习

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Introduction: Granulocytic sarcoma (GS) is a rare malignant neoplasia, with an incidence rate of 2.9% to 3.1% in patients with myeloid leukemia or myeloproliferative diseases. Usually it affects males, of African, Asian and South American populations. Objetive: To describe the radiological characteristics of GS in the face and skull of children and young people. Patients and methods: We report five patients with GS in the face and skull. Computerized tomography (CT) was carried out in four and orbital and brain magnetic resonance (MRI) in three. Out of the five, four had soft tissue masses in the orbit, two had bone infiltration, and in one there was a central nervous system lesion. In four patients acute myeloid leukemia was demonstrated. Conclusion: GS may affect the orbit, the face and the skull of children and young adults; it manifests with exophthalmia and orbital edema. It must be considered as a diagnostic possibility in the context of myeloid leukemia and myelodysplasias. Otherwise, differential diagnosis should be made with complications of sinusitis, orbital rhabdomyosarcoma, orbital lymphoma and other tumors. Imaging studies may help in the diagnosis by revealing soft tissue masses and areas of bone infiltration. In some cases GS may resemble abscesses. Diagnosis must be confirmed by histopathology.
机译:简介:粒细胞肉瘤(GS)是一种罕见的恶性肿瘤,在髓样白血病或骨髓增生性疾病患者中的发生率为2.9%至3.1%。通常,它影响非洲,亚洲和南美人口的男性。物体:描述儿童和年轻人面部和颅骨中GS的放射学特征。患者和方法:我们报告了5例面部和颅骨GS的患者。计算机断层扫描(CT)分为四部分,眼眶和脑磁共振(MRI)分为三部分。在五分之四的眼眶中有软组织肿块,两眼有骨浸润,其中一个有中枢神经系统病变。在四名患者中证实了急性髓细胞性白血病。结论:GS可能影响儿童和年轻人的眼眶,面部和颅骨;它表现为眼球突出和眼眶水肿。在骨髓性白血病和骨髓增生异常的情况下,必须将其视为诊断可能性。否则,应与鼻窦炎,眼眶横纹肌肉瘤,眼眶淋巴瘤和其他肿瘤的并发症进行鉴别诊断。影像学检查可通过显示软组织肿块和骨浸润区域来帮助诊断。在某些情况下,GS可能类似于脓肿。诊断必须通过组织病理学确认。

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