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首页> 外文期刊>Indian Journal of Dental Research >A comparative evaluation of transdermal diclofenac patch with oral diclofenac sodium as an analgesic drug following periodontal flap surgery: A randomized controlled clinical study
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A comparative evaluation of transdermal diclofenac patch with oral diclofenac sodium as an analgesic drug following periodontal flap surgery: A randomized controlled clinical study

机译：牙周皮瓣术后口服双氯芬酸钠作为镇痛药的双氯芬酸透皮贴剂的比较评价：随机对照临床研究

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Background: Pain is an inevitable outcome of any periodontal surgery. Controlling postoperative pain is of utmost importance so as to increase patient compliance. The present study aims to compare the degree of postoperative analgesia with the use of oral diclofenac sodium and transdermal diclofenac patch following periodontal flap surgery in patients with chronic periodontitis. Materials and Methods: A total of 20 patients requiring full mouth flap surgery were selected for this study. Flap surgery was performed quadrant-wise and transdermal diclofenac patch was applied on the right arm following surgery of one of the quadrants and 100 mg oral diclofenac sodium twice daily was prescribed following surgery of the subsequent quadrant. The postoperative pain was recorded on visual analog scale and pain intensity scale 24 h after the surgery. Results: Both the statistical and clinical observation showed that diclofenac sodium administered transdermally has equal efficacy as compared to drug administered orally. Conclusion: The study concludes that the diclofenac administered transdermally has equal potency in relieving postoperative pain as compared to orally administered diclofenac sodium following modified flap surgery. Transdermal patch has an added advantage of better patient compliance as it does not cause gastric disturbance.
机译：背景：疼痛是任何牙周手术的必然结果。控制术后疼痛至关重要，以增加患者的依从性。本研究旨在比较慢性牙周炎患者牙周皮瓣手术后口服双氯芬酸钠和透皮双氯芬酸贴剂的术后镇痛程度。材料和方法：总共选择20名需要全口瓣手术的患者。象限一次进行皮瓣手术，对一个象限进行手术后，在右臂上施用透皮双氯芬酸贴剂，并在随后的象限手术后开处方每日两次口服100 mg双氯芬酸钠。术后24小时以视觉模拟量表和疼痛强度量表记录术后疼痛。结果：统计学和临床​​观察均显示，与口服药物相比，双氯芬酸钠经皮给药具有相同的功效。结论：该研究得出结论，与改良皮瓣手术后口服双氯芬酸钠相比，双氯芬酸经皮给药具有缓解术后疼痛的同等效力。透皮贴剂还具有更好的患者依从性的优点，因为它不会引起胃部不适。

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