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首页> 外文期刊>Indian Journal of Medical Microbiology >Dynamics of the occurrence of influenza in relation to seasonal variation in Chennai, Tamil Nadu: A 7 -year cumulative study
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Dynamics of the occurrence of influenza in relation to seasonal variation in Chennai, Tamil Nadu: A 7 -year cumulative study

机译：泰米尔纳德邦金奈（Chennai）的流感发生动态与季节性变化的关系：一项为期7年的累积研究

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Background: Influenza viruses have emerged as virulent pathogens causing considerable burden across the world. A thorough understanding of the pattern in occurrence of influenza globally is the need of hour. The present study deals with analysis of the dynamics of Influenza virus, especially the influence of seasonal change on viral circulation and causation of epidemics/pandemics in the context of subtropical region. Methods: During the 7 year (2009–2015) study, 36670 specimens were subjected to influenza analysis. Nasopharyngeal swabs collected from suspected patients from Chennai, Tamil Nadu, were tested and typed by real-time polymerase chain reaction assay. Results: During 2009 pandemic, among influenza A positives 95.16% were Apdm09, indicating that there was a predominant circulation of Apdm09. During postpandemic period, there were waves in the occurrence of Apdm09 which indicates fall in immunity with buildup in the susceptible population. Conclusion: In Chennai, Tamil Nadu, influenza positivity started with the onset of monsoon and peaks during the postmonsoon months throughout the study period. The assessment of meteorological factors compounding influenza activity can help in raising alerts to the public health officials of impending disaster which suggests that Influenza vaccination can be initiated before monsoon months in South India.
机译：背景：流感病毒已作为强毒病原体出现，在世界范围内造成了相当大的负担。要全面了解全球流感的发生模式，需要几个小时。本研究涉及流感病毒的动力学分析，特别是在亚热带地区，季节性变化对病毒循环的影响以及流行病/大流行的原因。方法：在为期7年（2009-2015年）的研究中，对36670个标本进行了流感分析。通过实时聚合酶链反应测定法对从可疑患者中采集的来自泰米尔纳德邦金奈的疑似患者的鼻咽拭子进行了测试和分型。结果：在2009年的大流行中，Apdm09的A流感阳性阳性率为95.16％，这表明Apdm09的主要流行。在大流行后时期，Apdm09的出现出现了波动，这表明易感人群的免疫力随积累而下降。结论：在泰米尔纳德邦金奈，流感阳性始于季风的发作，并在整个研究期间的季风后数月达到峰值。评估与流感活动有关的气象因素可以帮助提高公共卫生官员对即将发生的灾难的警报，这表明可以在印度南部的季风月份之前开始接种流感疫苗。

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