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Awareness of changing trends in epidemiology of dengue fever is essential for epidemiological surveillance

机译:了解登革热流行病学变化趋势对于流行病学监测至关重要

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Dengue has become endemic in India with outbreaks occurring almost every year. The seroprevalence and serotypic data of the last 7 years in samples obtained from suspected dengue patients from a tertiary care hospital were analyzed. Out of 7846 serum samples received in the virology laboratory from suspected dengue cases during 2002 to 2008, 2366 (30.15%) were serologically confirmed. Serotyping was done using mRT-PCR. All the four serotypes were detected in 2003, while data in 2004, 2005 and 2006 revealed the the predominance of Den-3. In the year 2007 predominance of Den-2 was observed, whereas in 2008 Den-1 was the most common serotype isolated. Overall, Den-2 and Den-3 were the most predominant serotypes during 2003-2007 but Den-1 replaced these strains in the year 2008. Since the emergence of a new predominant strain can lead to the occurrence of an outbreak, presence of Den-1 in the year 2008 would pose an alarming situation before us. Well-targeted population-based epidemiological studies are urgently required to control dengue menace.
机译:登革热已在印度流行,几乎每年都在爆发。分析了从一家三级医院的疑似登革热患者那里获得的样本中最近7年的血清阳性率和血清型数据。从病毒学实验室在2002年至2008年期间从疑似登革热病例中获得的7846份血清样品中,有2366份(30.15%)被血清学确认。使用mRT-PCR进行血清分型。所有四种血清型均在2003年被检测到,而2004、2005和2006年的数据显示出Den-3的优势。在2007年,发现了Den-2优势,而在2008年,Den-1是最常见的血清型。总体而言,在2003-2007年间,Den-2和Den-3是最主要的血清型,但Den-1在2008年取代了这些菌株。由于新的主要菌株的出现可能导致爆发发生,因此Den -1在2008年将摆在我们面前的情况令人震惊。迫切需要针对性强的基于人群的流行病学研究,以控制登革热的威胁。

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