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A study of organisms causing surgical site infections and their antimicrobial susceptibility in a tertiary care Government Hospital

机译:三级护理政府医院中引起手术部位感染的生物及其抗菌药敏性的研究

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Background: Surgical site infection (SSI) is one of the most common postoperative complication and causes significant postoperative morbidity and mortality. Patients: A prospective study was carried out in a total of 100 patients operated for clean and clean-contaminated surgeries from department of orthopedics, surgery and obstetrics & gynecology. Materials and Methods: Relevant details were noted in clinical history. Each patient was followed from the time of admission till discharge from the hospital and also for 30 days postoperatively (CDC, 1999). The identification of the infecting organism was done by staining, and culture and antibiotic susceptibility by Disc Diffusion method. Results: Out of 100 patients, 32 patients got infected post-operatively. Staphylococcus aureus was the most common organism isolated. None of the strains were Methicillin resistant. Drug resistance was widespread, especially in Enterobacteriaceae, where the Cefotaxime resistant strains of Escherichia coli and Klebsiella pneumoniae were ESBL producing. Another concern in recent times is the isolation of Acinetobacter from surgical wounds. Various patient factors and hospital protocol were analyzed with regard to the treatment outcome. Judicious use of antibiotics along with evidence-based medicine is the need of the hour to stop the rise of these superbugs.
机译:背景:手术部位感染(SSI)是最常见的术后并发症之一,并导致明显的术后发病率和死亡率。患者:整形外科,外科以及妇产科的100例接受清洁手术的患者均进行了一项前瞻性研究。材料和方法:在临床病史中记录了相关细节。从入院到出院,以及术后30天,对每位患者进行随访(CDC,1999)。通过染色进行感染生物的鉴定,通过圆盘扩散法进行培养和抗生素敏感性的鉴定。结果:100例患者中,有32例术后感染。金黄色葡萄球菌是最常见的分离生物。所有菌株均不耐甲氧西林。耐药性普遍存在,尤其是在肠杆菌科,其中大肠杆菌和肺炎克雷伯菌的头孢噻肟耐药菌株均产生ESBL。近来的另一关注是从手术伤口中分离不动杆菌。就治疗结果分析了各种患者因素和医院方案。数小时之内就需要停止使用抗生素以及循证医学来阻止这些超级细菌的出现。

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