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Pharmacovigilance: pharmacists’ perspective on spontaneous adverse drug reaction reporting

机译:药物警戒:药剂师对自发不良药物反应报告的看法

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Globally, adverse drug reactions (ADRs), one of the leading causes of morbidity and mortality, will continue to pose a threat to public health as long as drugs are being used to treat various ailments. Prompt ADR reporting is crucial in ensuring drug safety. The aim of this narrative review was to highlight the role of pharmacists in pharmacovigilance and to identify barriers and facilitators toward ADR reporting documented in the literature. The perspective of pharmacy students on pharmacovigilance and ADR reporting has also been discussed with an aim to highlight the need to improve content related to ADR reporting and pharmacovigilance in undergraduate pharmacy curriculum. Globally, although the role of pharmacists within national pharmacovigilance systems varies, it is very well recognized. In general, pharmacists acknowledge that ADR reporting is part of their professional responsibility and have a positive attitude toward reporting ADRs. However, current research evidence suggests that there are still critical knowledge gaps with regard to ADR reporting among pharmacists, especially in countries where the role of pharmacists within the health care system is limited. These knowledge gaps can be fulfilled through continuous professional development programs and reinforcing theoretical and practical knowledge in undergraduate pharmacy curriculums. Without adequately identifying and fulfilling training needs of pharmacists and other health care professionals, the efficiency of national pharmacovigilance systems is unlikely to improve which may compromise patient’s safety.
机译:在全球范围内,药物不良反应(ADR)是发病率和死亡率的主要原因之一,只要药物被用于治疗各种疾病,就会继续对公共健康构成威胁。及时的ADR报告对于确保药物安全至关重要。这篇叙述性综述的目的是强调药剂师在药物警戒中的作用,并找出阻碍文献记载的ADR报告的障碍和促进者。还讨论了药房学生对药物警戒和ADR报告的观点,目的是强调需要提高本科药房课程中与ADR报告和药物警戒有关的内容。在全球范围内,尽管药剂师在国家药物警戒系统中的作用各不相同,但这一点已得到公认。通常,药剂师承认ADR报告是其专业职责的一部分,并且对报告ADR持积极态度。但是,当前的研究证据表明,在药剂师之间,尤其是在医疗保健系统中药剂师的作用受到限制的国家中,在ADR报告方面仍然存在严重的知识差距。这些知识差距可以通过持续的专业发展计划以及在本科药学课程中加强理论和实践知识来弥补。如果没有充分确定和满足药剂师和其他卫生保健专业人员的培训需求,国家药物警戒系统的效率就不可能提高,这可能会损害患者的安全。

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