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Impact of obesity on male fertility

机译：肥胖对男性生育的影响

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Rationale Nowadays, obesity and dyslipidemia are more prevalent , studies had shown that obese men have around 50% higher rate of infertility compared to normal weight men Aim of the work is to study the impact of obesity on male infertility Subjects and methods This study included 90 males aged ( 25 - 45 ) years old , divided into three groups . Semen samples to assess semen quality plus a blood sample to measure serum testosterone and leptin levels were collected Results A statistically significant increases of mean BMI in obese fertile and obese infertile groups compared to non-obese infertile group (p. < 0.0001) .There was a statistically significant increase of mean serum leptin in obese infertile group compared to obese fertile group (p. < 0.0001) and compared to obese fertile group (p. < 0.0001). There was a statistically significant increase of mean serum testosterone level in obese fertile group compared to non-obese infertile group (p < 0.01) and there was a statistically significant increase of mean sperm motility in obese fertile group compared to obese infertile group Conclusion. BMI & serum leptin levels in obese infertile men were significantly higher than obese fertile men. Serum leptin had significant negative correlation with sperm count, motility and testosterone level. Leptin had significant correlation with the abnormal sperm morphology. Men with high BMIs had a significant decrease in sperm count, and motility as well as increase in the abnormal forms of spermatozoa compared to those with low BMIs. Keywords : Obesity, Infertility, Semen Quality, Testosterone, Leptin.
机译：基本原理如今，肥胖和血脂异常更为普遍，研究表明，与正常体重的男性相比，肥胖男性的不育率高约50％。目的是研究肥胖对男性不育的影响受试者和方法该研究包括90男性（25-45岁），分为三组。结果，与未肥胖组相比，肥胖可育组和肥胖不育组的平均BMI有统计学意义的显着增加（p。<0.0001）。有评估精液质量的精液样本和测量血清睾丸激素和瘦素水平的血液样本。与肥胖可育组（p <0.0001）和肥胖可育组（p。<0.0001）相比，肥胖不育组的平均血清瘦素水平有统计学意义的增加。与非肥胖不育组相比，肥胖可育组的平均血清睾丸激素水平有统计学意义的增加（p <0.01），并且与肥胖不育组相比，肥胖可育组的平均精子活力有统计学意义的结论。肥胖不育男性的BMI和血清瘦素水平显着高于肥胖可育男性。血清瘦素与精子数量，运动能力和睾丸激素水平呈显着负相关。瘦素与精子形态异常显着相关。与低BMI的男性相比，BMI高的男性的精子数量，运动能力以及精子异常形式的增加显着减少。关键词：肥胖，不育，精液质量，睾丸激素，瘦素。

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