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首页> 外文期刊>International Journal of Basic Medical Sciences and Pharmacy >Phytochemical screening, antimicrobial and cytotoxic activity of different fractions of Sesbania sesban bark
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Phytochemical screening, antimicrobial and cytotoxic activity of different fractions of Sesbania sesban bark

机译：Sesbania sesban树皮不同级分的植物化学筛选，抗菌和细胞毒性活性

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In Bangladesh, the tree Sesbania sesban (L) Merr. is used as the traditional medicine for the treatment of a number of ailments. The present study has been undertaken for antimicrobial activity of the ethanol, ether (diethyl ether) and chloroform extracts of S. sesban bark. Antimicrobial activity has been investigated against five Gram-positive bacteria, nine Gram-negative bacteria and seven fungi by disc diffusion and broth macro-dilution assay. The zone of inhibition has been observed with almost all bacteria and fungi with some exceptions. Minimum inhibitory concentrations (MIC) of these extracts were found to be significant. In brine shrimp lethality bioassay test, the LC50 values of ethanol, ether and chloroform extracts of bark of S. sesban were found to be 1280, 640 and 320 μg/ml, respectively. Findings of the study justify the use of the plant in traditional medicine and suggests for further investigation.
机译：在孟加拉国，Sesbania sesban（L）Merr树。被用作治疗多种疾病的传统药物。本研究已针对苏塞巴树皮的乙醇，乙醚（二乙醚）和氯仿提取物的​​抗菌活性进行了研究。通过椎间盘扩散和肉汤大量稀释试验研究了对五种革兰氏阳性细菌，九种革兰氏阴性细菌和七种真菌的抗菌活性。除某些例外，几乎所有细菌和真菌都观察到了抑制区域。发现这些提取物的最低抑菌浓度（MIC）很高。在盐水虾杀伤力生物测定法测试中，S。sesban树皮的乙醇，乙醚和氯仿提取物的​​LC50值分别为1280、640和320μg/ ml。这项研究的发现证明了该植物在传统医学中的用途，并建议进一步研究。

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