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Phytochemical Screening and Antimicrobial Activity of Leaf and Stem-bark Aqueous Extracts of Diospyros mespiliformis

机译:盾叶薯os叶和茎皮水提物的植物化学筛选及其抑菌活性

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Objective: To investigates the phytochemical composition and antimicrobial activities of the leaf and stem-bark extracts of D. mespiliformis against some pathogenic microorganisms. Methods: The leaf and stem-bark extracts of Diospyros mespiliformis from Ebanaceae family, which is used as herbal remedies for the cure of many ailments by natives in northern part of Nigeria, were collected from Mubi in Mubi North Local Government area of Adamawa State, air dried, pulverised, extracted by simple overnight maceration techniques and analyzed. Aqueous extracts of the aforementioned parts of the plant were screened phytochemically for its chemical constituents and subjected to antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Shigella spp, Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyogenes and Salmonella typhi. Results: The results show that alkaloids, anthraquinones, carbohydrates, flavonoids, phlobatannins, saponins, steroids, tannins and terpenoids are present in both the leaf and the stem-bark extracts of the plant while glycosides are present in the leaf extract but absent in the stem-bark extract. The antimicrobial activity reveals that both the leaf and the stem-bark extracts of the plant, showed high sensitivity to Escherichia coli, Pseudomonas aeruginosa, Shigella spp, Staphylococcus aureus, Streptococcus pneumonia, Streptococcus pyogenes and Salmonella typhi. Conclusion: The phytochemical constituents and the antimicrobial potential of the plant part may account for varied ethnobotanical uses of the plants in traditional medicine in Nigeria, which if further purified can be used to source novel antibiotics.
机译:目的:研究介孢石。叶和茎皮提取物对某些病原微生物的植物化学组成和抑菌活性。方法:从阿巴纳瓦州穆比北地方政府地区的穆比(Mubi)收集了埃巴纳科(Ebanaceae)的盾叶蝉(Diospyros mespiliformis)的叶和茎皮提取物,作为草药用于治疗尼日利亚北部土著人的多种疾病。风干,粉碎,通过简单的浸渍法提取并分析。对植物上述部分的水提物进行植物化学筛选,并对其化学成分进行筛选,并对大肠杆菌,铜绿假单胞菌,志贺氏菌,金黄色葡萄球菌,肺炎链球菌,化脓性链球菌和伤寒沙门氏菌进行抗菌活性。结果:结果表明,植物的叶片和茎皮提取物中均存在生物碱,蒽醌,碳水化合物,类黄酮,间巴单宁,皂角苷,类固醇,单宁和萜类化合物,而叶片提取物中却存在糖苷,而植物中没有糖苷。茎皮提取物。抗菌活性表明,该植物的叶子和茎皮提取物均对大肠杆菌,铜绿假单胞菌,志贺氏菌,金黄色葡萄球菌,肺炎链球菌,化脓性链球菌和鼠伤寒沙门氏菌表现出很高的敏感性。结论:尼日利亚传统医学中植物部分的植物化学成分和抗菌潜力可能解释了植物在植物学上的多种用途,如果进一步纯化,则可以用于寻找新的抗生素。

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