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首页> 外文期刊>International Journal of Biochemistry Research & Review >Investigation of Biochemical Parameters inBurkinabese Local Small Ruminants BreedNaturally Infected with Trypanosomosis
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Investigation of Biochemical Parameters inBurkinabese Local Small Ruminants BreedNaturally Infected with Trypanosomosis

机译：自然感染锥虫病的布吉纳布斯当地小型反刍动物的生化参数研究

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Aims: This study aimed at establishing standard values of some biochemical parameters in Burkinabese small ruminants’ breeds and their changes due to the infection of trypanosomes. This work helps determine the prevalence of trypanosomosis in small ruminants in the study area.Materials and Methods: A total of 317 small ruminants (173 sheep and 144 goats) were sampled for cross sectional survey of trypanosomosis from 10 villages of the agro pastoral zone of Sideradougou in the southern of Burkina Faso in July 2010. The parasitological analysis was carried out by microscopy according the Buffy Coat Technique (BCT). The biochemical parameters were analyzed using commercial kits (BIOSYSTEMS? SA). Results: The overall parasitological prevalence was 5.99%. Infections were due to T. congolense and T. vivax with predominance of the latter (68.42% of cases). The values of biochemical parameters found in sheep and goats were within the ranges of physiological values. However, these values varied with age and trypanosomosis infection status. In young animals for both species, cholesterol and magnesium values were significantly lower than the adult subjects. Various biochemical parameters related to nutritional status were lower in young and trypanosome infected animals than in adults and healthy animals, respectively. The values of total proteins were significantly higher in the infected goats than healthy ones (p=0.001), while the contrary was observed in sheep. The gamma globulin values were significantly increased in the trypanosome infected subjects (p<0.001 in goats).Conclusion: Trypanosmosis infection induced changes in the values of some biochemical parameters in small ruminants. The results of this study could help clinicians to improve the diagnosis of diseases in local small ruminants’ breeds by good interpretation of biochemical analyses.
机译：目的：本研究旨在确定布基纳法索小型反刍动物品种中某些生化参数的标准值，以及因锥虫感染而引起的变化。这项工作有助于确定研究区域内小型反刍动物的锥虫病患病率。材料与方法：共采集了317个小反刍动物（173只绵羊和144只山羊）的横断面调查，用于该地区农牧区10个村庄的锥虫病横断面调查。 2010年7月，在布基纳法索南部的Sideradougou。根据显微镜下的Buffy Coat技术（BCT），进行了寄生虫学分析。使用商业试剂盒（BIOSYSTEMS？SA）分析生化参数。结果：总体寄生虫患病率为5.99％。感染是由于锥虫和间日疟原虫的感染（占病例总数的68.42％）。在绵羊和山羊中发现的生化参数值在生理值范围内。但是，这些值随年龄和锥虫病感染状况而变化。在这两种动物的幼小动物中，胆固醇和镁的含量均显着低于成年个体。与营养状态有关的各种生化参数在成年和锥虫感染的动物中分别低于成年和健康动物。被感染山羊的总蛋白值显着高于健康山羊（p = 0.001），而在绵羊中则相反。在受锥虫感染的受试者中，γ球蛋白值显着增加（山羊为p <0.001）。结论：锥虫病感染导致小型反刍动物某些生化参数值发生变化。这项研究的结果可以通过对生化分析的良好解释来帮助临床医生改善当地小型反刍动物品种的疾病诊断。

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