Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer?

Kenneth D.Westover; M. BrandonWestover; Eric P.Winer; Andrea L.Richardson; J. DirkIglehart; Rinaa S.Punglia

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Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer?

机译：高危乳腺癌患者应进行前哨淋巴结活检吗？

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A negative sentinel lymph node (SLN) biopsy spares many breast cancer patients the complications associated with lymph node irradiation or additional surgery. However, patients at high risk for nodal involvement based on clinical characteristics may remain at unacceptably high risk of axillary disease even after a negative SLN biopsy result. A Bayesian nomogram was designed to combine the probability of axillary disease prior to nodal biopsy with customized test characteristics for an SLN biopsy and provides the probability of axillary disease despite a negative SLN biopsy. Users may individualize the sensitivity of an SLN biopsy based on factors known to modify the sensitivity of the procedure. This tool may be useful in identifying patients who should have expanded upfront exploration of the axilla or comprehensive axillary irradiation.

机译：前哨淋巴结（SLN）活检阴性使许多乳腺癌患者避免了与淋巴结照射或其他手术相关的并发症。但是，即使在SLN活检结果阴性后，基于临床特征而有较高的淋巴结转移风险的患者仍可能处于无法接受的腋窝疾病高风险中。贝叶斯诺模图被设计为将淋巴结活检之前的腋窝疾病概率与SLN活检的定制测试特征相结合，并提供SLN活检阴性的腋窝疾病概率。用户可以根据已知会修改手术敏感性的因素来个性化SLN活检的敏感性。该工具对于识别应扩大腋窝或全面腋窝照射的患者可能有用。

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《International Journal of Breast Cancer》 |2011年第4期|共5页
作者
Kenneth D.Westover; M. BrandonWestover; Eric P.Winer; Andrea L.Richardson; J. DirkIglehart; Rinaa S.Punglia;
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中图分类临床医学;
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1. The value of breast MRI in high-risk patients with newly diagnosed breast cancer to exclude invasive disease in the contralateral prophylactic mastectomy: Is there a role to choose wisely patients for sentinel node biopsy? [J] . Marcela de Abreu Moniz, Pierre Vila, Karina Bukhanov, Cancer Medicine . 2016,第6期

机译：在对侧预防性乳房切除术中，乳腺MRI在高危新诊断乳腺癌中排除浸润性疾病的价值：明智地选择前哨淋巴结活检的患者是否有作用？
2. A longitudinal comparison of arm morbidity in stage I-II breast cancer patients treated with sentinel lymph node biopsy, sentinel lymph node biopsy followed by completion lymph node dissection, or axillary lymph node dissection. [J] . Kootstra JJ, Hoekstra Weebers JE, Rietman JS, Annals of surgical oncology . 2010,第9期

机译：对前哨淋巴结活检，前哨淋巴结活检然后完成淋巴结清扫或腋窝淋巴结清扫术治疗的I-II期乳腺癌患者的手臂发病率进行纵向比较。
3. The Shift From Sentinel Lymph Node Biopsy Performed Either Before or After Neoadjuvant Systemic Therapy in the Clinical Negative Nodes of Breast Cancer Patients. Results, and the Advantages and Disadvantages of Both Procedures [J] . Sergi Fernandez-Gonzalez, Catalina Falo, Maria Jesus Pla, Clinical breast cancer . 2018,第1期

机译：在乳腺癌患者的临床负节点中，在Neoadjuvant全身治疗之前或之后进行的Sentinel淋巴结活检的转变。结果，以及两种程序的优缺点
4. Magnetic-Particle-Imaging for Sentinel Lymph Node Biopsy in Breast Cancer [C] . Ksenija Grafe, Timo F. Sattel, Kerstin Ludtke-Buzug, International Workshop on Magnetic Particle Imaging . 2012

机译：乳腺癌中Sentinel淋巴结活检的磁性粒子成像
5. Evaluation of pathologic parameters and published nomograms in predicting non-sentinel lymph node metastases in female breast cancer patients with positive sentinel lymph nodes. [D] . Murch, Lisa Elaine. 2007

机译：在前哨淋巴结阳性的女性乳腺癌患者中预测非前哨淋巴结转移的病理参数和公布的列线图评估。
6. Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer? [O] . Kenneth D. Westover, M. Brandon Westover, Eric P. Winer, 2011

机译：高危乳腺癌患者应进行前哨淋巴结活检吗？
7. Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer? [O] . Westover, Kenneth D., Westover, M. Brandon, Winer, Eric P., 2011

机译：高危乳腺癌患者应进行前哨淋巴结活检吗？

Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer?

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