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Electrochemical Analysis of Tanshinone IIA in Salvia Based on Chitosan-coated Graphene

机译:壳聚糖包覆石墨烯对丹参中丹参酮ⅡA的电化学分析

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In this work, tanshinone IIA (TAN) was successfully detected using an effective and facile electrochemical sensor based on an RGO/Au (reduced graphene oxide/gold nanoparticle)-modified electrode. RGO was prepared using a microwave-assisted technique. For the preparation of the RGO/Au nanocomposite, Au nanoparticles were electrodeposited onto the surface of RGO. The electrochemical response of the sensor to TAN reduction was investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The electrochemical activity of TAN is significantly enhanced when using the RGO/Au-modified GCE. Our sensor shows a desirable linear response to TAN concentration in the range of 0.01 - 10 μM. Furthermore, the sensor shows potential for use in the determination of TAN in Salvia extract samples.
机译:在这项工作中,使用基于RGO / Au(还原的氧化石墨烯/金纳米粒子)修饰的电极的高效便捷的电化学传感器成功检测了丹参酮IIA(TAN)。 RGO是使用微波辅助技术制备的。为了制备RGO / Au纳米复合材料,将Au纳米颗粒电沉积到RGO的表面上。使用循环伏安法(CV)和电化学阻抗谱(EIS)研究了传感器对TAN还原的电化学响应。当使用RGO / Au修饰的GCE时,TAN的电化学活性显着增强。我们的传感器对TAN浓度在0.01-10μM范围内表现出理想的线性响应。此外,该传感器显示出用于测定丹参提取物样品中TAN的潜力。

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