...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Electrochemistry >Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode
【24h】

Stripping Voltammetric Determination of Analgesics in Their Pharmaceuticals Using Nano-Riboflavin-Modified Glassy Carbon Electrode

机译：纳米核黄素修饰的玻碳电极溶出伏安法测定药物中的止痛剂

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cyclic voltammetric behaviors of three analgesics, acetaminophen (AAP), acetylsalicylic acid (ASA), and dipyrone (DP), were studied using nano-riboflavin-modified glassy carbon electrode. One well-defined oxidation peak each for AAP and ASA and three oxidation peaks for DP were observed. The influence of pH, scan rate, and concentration reveals irreversible diffusion controlled reaction. The SEM analysis confirmed good accumulation of the drugs on the electrode surface. Calibration was made under the maximum peak current conditions. The concentration range studied for the determination of drugs was 0.02 to 0.4 μg mL−1for AAP and ASA and 0.025 to 0.4 μg mL−1for DP. The lower limit of detection observed for AAP, ASA, and DP was 0.016, 0.007 μg mL−1, and 0.013 μg mL−1, respectively. The suitability of the method for the determination of these analgesics in pharmaceutical preparations and urine samples was also ascertained.
机译：使用纳米核黄素修饰的玻碳电极研究了三种镇痛药对乙酰氨基酚（AAP），乙酰水杨酸（ASA）和双嘧啶（DP）的循环伏安行为。观察到一个清晰定义的AAP和ASA氧化峰，三个DP氧化峰。 pH，扫描速率和浓度的影响揭示了不可逆的扩散控制反应。 SEM分析证实了药物在电极表面上的良好积累。在最大峰值电流条件下进行校准。用于药物测定的浓度范围对于AAP和ASA为0.02至0.4μg/ mL-1，对于DP为0.025至0.4μg/ mL-1。 AAP，ASA和DP的检测下限分别为0.016、0.007μg / mL-1和0.013μg/ mL-1。还确定了用于确定这些止痛剂在药物制剂和尿液样品中的方法的适用性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号