...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Environmental Research and Public Health >Long Non-Coding RNA as Potential Biomarker for Prostate Cancer: Is It Making a Difference?
【24h】

Long Non-Coding RNA as Potential Biomarker for Prostate Cancer: Is It Making a Difference?

机译：较长的非编码RNA作为前列腺癌的潜在生物标记物：它会有所作为吗？

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Whole genome transcriptomic analyses have identified numerous long non-coding RNA (lncRNA) transcripts that are increasingly implicated in cancer biology. LncRNAs are found to promote essential cancer cell functions such as proliferation, invasion, and metastasis, with the potential to serve as novel biomarkers of various cancers and to further reveal uncharacterized aspects of tumor biology. However, the biological and molecular mechanisms as well as the clinical applications of lncRNAs in diverse diseases are not completely understood, and remain to be fully explored. LncRNAs may be critical players and regulators in prostate cancer carcinogenesis and progression, and could serve as potential biomarkers for prostate cancer. This review focuses on lncRNA biomarkers that are already available for clinical use and provides an overview of lncRNA biomarkers that are under investigation for clinical development in prostate cancer.
机译：全基因组转录组学分析已鉴定出许多长的非编码RNA（lncRNA）转录本，这些转录本越来越与癌症生物学有关。发现LncRNA可以促进癌细胞的基本功能，例如增殖，侵袭和转移，并具有作为各种癌症的新生物标记并进一步揭示肿瘤生物学未表征方面的潜力。然而，lncRNAs在多种疾病中的生物学和分子机制以及临床应用尚不完全清楚，有待充分探索。 LncRNAs可能是前列腺癌致癌性和发展过程中的关键参与者和调节者，并且可以作为前列腺癌的潜在生物标志物。这篇综述着重于已经可用于临床的lncRNA生物标志物，并概述了正在研究前列腺癌临床发展的lncRNA生物标志物。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号