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首页> 外文期刊>International Journal of Environmental Research and Public Health >Multilevel Analysis of Air Pollution and Early Childhood Neurobehavioral Development
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Multilevel Analysis of Air Pollution and Early Childhood Neurobehavioral Development

机译：空气污染与幼儿神经行为发育的多层次分析

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摘要

To investigate the association between the ambient air pollution levels during the prenatal and postnatal stages and early childhood neurobehavioral development, our study recruited 533 mother-infant pairs from 11 towns in Taiwan. All study subjects were asked to complete childhood neurobehavioral development scales and questionnaires at 6 and 18 months. Air pollution, including particulate matter ≤10 μm (PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and hydrocarbons, was measured at air quality monitoring stations in the towns where the subjects lived. Multilevel analyses were applied to assess the association between air pollution and childhood neurobehavioral development during pregnancy and when the children were 0 to 6 months, 7 to 12 months, and 13 to 18 months old. At 18 months, poor subclinical neurodevelopment in early childhood is associated with the average SO2 exposure of prenatal, during all trimesters of pregnancy and at postnatal ages up to 12 months (first trimester β = ?0.083, se = 0.030; second and third trimester β = ?0.114, se = 0.045; from birth to 12 months of age β = ?0.091, se = 0.034). Furthermore, adverse gross motor below average scores at six months of age were associated with increased average non-methane hydrocarbon, (NMHC) levels during the second and third trimesters (β = ?8.742, se = 3.512). Low-level SO2 exposure prenatally and up to twelve months postnatal could cause adverse neurobehavioral effects at 18 months of age. Maternal NMHC exposure during the 2nd and 3rd trimesters of pregnancy would be also associated with poor gross motor development in their children at 6 months of age.
机译：为了调查产前和产后阶段的环境空气污染水平与幼儿神经行为发育之间的关系，我们的研究从台湾11个城镇招募了533对母婴。要求所有研究对象在6和18个月时完成儿童神经行为发育量表和问卷调查。在以下城市的空气质量监测站测量了空气污染，包括≤10μm的颗粒物（PM10），一氧化碳（CO），二氧化硫（SO2），二氧化氮（NO2），臭氧（O3）和碳氢化合物。被试住了。应用多级分析来评估空气污染与怀孕期间以及儿童0至6个月，7至12个月和13至18个月大时儿童神经行为发展之间的关系。在18个月时，儿童早期亚临床神经发育不良与妊娠前三个月以及出生后12个月的产前平均SO2暴露相关（孕中期β=≤0.083，se = 0.030;孕中期和孕中期β = = 0.114，se = 0.045;从出生到12个月大时，β= = 0.091，se = 0.034）。此外，在六个月大时，不良的总运动能力低于平均得分与中，晚期三个月的平均非甲烷碳氢化合物（NMHC）水平升高相关（β= 8.7 8.742，se = 3.512）。产前和产后长达十二个月的低水平二氧化硫暴露可能在18个月大时引起不良的神经行为影响。孕妇在妊娠的第2和第3个月暴露于NMHC也可能与6个月大的孩子运动能力差有关。

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