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首页> 外文期刊>International Journal of Environmental Research and Public Health >Dietary Patterns Associated with Alzheimer’s Disease: Population Based Study
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Dietary Patterns Associated with Alzheimer’s Disease: Population Based Study

机译：与阿尔茨海默氏病相关的饮食模式：基于人群的研究

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Recently dietary pattern analysis has emerged as a way for examining diet-disease relations in Alzheimer’s disease. In contrast with the conventional approach, which focuses on a single nutrient or a few nutrients or foods, this method considers overall eating patterns. We examined the dietary patterns defined by factor analysis using data collected with a food-frequency questionnaire in people with Alzheimer’s disease (AD) as compared to healthy controls. The diet data were obtained during population based study of the prevalence of Alzheimer’s disease in a population in Poland. Stratified sampling and random selection strategies were combined to obtain a representative population for screening (age group > 55). From the population screened three times, 71 people were diagnosed with Alzheimer’s according to DSM-IV, and were recruited for further diet risk factors assessment. A group of people with Alzheimer disease (n = 71; F/M 42/29) and the same number of healthy, age and gender matched control were recruited for the study. Patients and their caregivers as well as controls were presented with a food frequency questionnaire based on the 12 food groups. Factor analysis (principal component) was used to derive food patterns. The analysis was conducted using the factor procedure. The factors were rotated by an orthogonal transformation (Varimax rotation) to achieve simpler structure with greater interpretability. Using factor analysis, we identified major eating patterns, one for Alzheimer’s patients and a different one for control group. The AD dietary pattern, FACTOR AD was characterized by a high intake of meat, butter, high-fat dairy products, eggs, and refined sugar, whereas the other pattern, (FACTOR C) was characterized by a high intake of grains and vegetables. These data indicate the existence of dietary patterns defined by factor analysis with data from a food frequency questionnaire, characteristic for Alzheimer’s disease in a Polish population.
机译：最近，饮食模式分析已成为一种检查阿尔茨海默氏病饮食与疾病关系的方法。与传统方法侧重于单一营养素或少量营养素或食物的方法相反，该方法考虑了整体饮食方式。我们使用食物频率调查表收集的数据，与健康对照组相比，通过饮食频率调查问卷调查了通过因素分析确定的饮食模式。饮食数据是在对波兰人口中的阿尔茨海默氏病患病率进行基于人群的研究期间获得的。分层抽样和随机选择策略相结合，以获得具有代表性的筛查人群（年龄组> 55）。根据DSM-IV，从经过3次筛查的人群中，有71人被诊断出患有阿尔茨海默氏症，并被招募进进进行饮食风险因素评估。该研究招募了一组患有阿尔茨海默氏病（n = 71; F / M 42/29）以及相同数量的健康，年龄和性别相匹配的对照的人。患者和他们的照顾者以及对照者接受了基于12个食物组的食物频率问卷调查。因子分析（主要成分）用于得出食物类型。使用因子程序进行分析。通过正交变换（Varimax旋转）旋转因子，以实现具有更高解释性的更简单结构。通过因素分析，我们确定了主要的饮食方式，一种用于阿尔茨海默氏症患者，另一种用于对照组。 AD饮食模式FACTOR AD的特征是大量摄入肉，黄油，高脂乳制品，鸡蛋和精制糖，而另一种饮食模式（FACTOR C）的特征是大量摄入谷物和蔬菜。这些数据表明存在通过因素分析定义的饮食模式，这些饮食模式来自食物频率问卷调查的数据，该数据是波兰人群中阿尔茨海默氏病的特征。

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