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首页> 外文期刊>International Journal of Environmental Research and Public Health >Association of Consecutive Influenza Vaccinations and Pneumonia: A Population-Based Case-Control Study
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Association of Consecutive Influenza Vaccinations and Pneumonia: A Population-Based Case-Control Study

机译：连续流感疫苗接种与肺炎的协会：基于人群的病例对照研究

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摘要

The purpose of this study was to investigate whether individuals receiving influenza vaccines have a lower risk of pneumonia. A nationwide population-based case-control study was conducted using data from the National Health Insurance Research Database in Taiwan. We enrolled 7565 patients each in pneumonia and non-pneumonia groups after diagnosis of patients with chronic pulmonary disease, and these patients were individually age and sex matched in a 1:1 ratio. Using conditional logistic regression analysis, adjusted odds ratios (aORs) were estimated in patients who received influenza vaccination and those who had not previously had pneumonia. Moreover, we also analyzed the interval between vaccination and the onset of pneumonia and the number of vaccinations received by patients. This was compared with patients who never received influenza vaccination. Patients who had received influenza vaccination and had been vaccinated for two consecutive years (aOR = 0.85, confidence interval (CI) = 0.79–0.93 and aOR = 0.75, CI = 0.67–0.85, respectively) showed lower rates of pneumonia occurrence by 15–25%. In conclusion, influenza vaccination significantly reduces the occurrence of pneumonia, especially in individuals who receive vaccination in consecutive years.
机译：这项研究的目的是调查接受流感疫苗的个人是否具有较低的肺炎风险。利用台湾国家健康保险研究数据库中的数据进行了全国性的基于病例的病例对照研究。在确诊患有慢性肺部疾病的患者后，我们分别将7565例肺炎和非肺炎患者纳入研究，这些患者的年龄和性别分别以1：1的比例匹配。使用条件对数回归分析，估计接受流感疫苗接种的患者和以前未曾患过肺炎的患者的校正比值比（aOR）。此外，我们还分析了疫苗接种与肺炎发作之间的间隔以及患者接受的疫苗接种次数。将其与从未接受流感疫苗接种的患者进行比较。接受流感疫苗接种并连续两年接种疫苗的患者（分别为aOR = 0.85，置信区间（CI）= 0.79–0.93和aOR = 0.75，CI = 0.67–0.85）显示肺炎发生率降低了15– 25％。总之，流感疫苗接种显着减少了肺炎的发生，特别是在连续几年接受疫苗接种的个体中。

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