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Exercise in Individuals with Down Syndrome: A Brief Review

机译：唐氏综合症患者的运动：简述

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International Journal of Exercise Science 8(2): 192-201, 2015. Research examining acute and long-term responses to exercise of individuals with Downs Syndrome (DS) is sparse. However, if this group experiences benefits associated with improved quantity or quality of life, it would be important to elucidate specific responses and discourage adoption of a sedentary lifestyle in individuals with DS. Specifically, these individuals have multiple blunted physiological responses to exercise both at the onset and termination of an acute exercise bout. Mechanistically, this could be rooted in hormonal responses which are blunted, in comparison to non-DS participants. Specific studies indicate individuals with DS appear to experience benefits in such hormonal responses, in response to short term (~12 weeks) participation in exercise programs. Damage due to oxidative stress is greater in individuals with DS, as the gene for superoxide dismutase lies on chromosome 21. Current research suggests exercise training can also improve oxidative stress in this population. Although less well-understood, there is potential for improved motor learning in individuals with DS as a result of exercise participation. This paper provides a brief review discussing current research on how individuals with DS respond to exercise. Further, a link is made advocating that blunted acute responses may result in elevated perceptions regarding difficulty of exercise, which in turn contributes to increased likelihood of having a sedentary lifestyle. Adverse effects have not been identified, and with no theoretical arguments against exercise participation, it is concluded that adaptive exercise programs for individuals with DS should be implemented for improving health and quality of life.
机译：国际运动科学杂志8（2）：192-201，2015年。研究唐氏综合症（DS）个体对运动的急性和长期反应的研究稀疏。但是，如果该组受益于改善数量或生活质量的好处，那么阐明特定的反应并劝阻DS患者不要采用久坐的生活方式，这一点很重要。具体而言，这些人在急性运动发作的开始和结束时具有多种钝化的生理反应以进行运动。从机理上讲，与非DS参与者相比，这可能是由于激素反应迟钝。特定研究表明，DS患者似乎在短期（约12周）参与锻炼计划后，会在这种激素反应中受益。由于超氧化物歧化酶的基因位于21号染色体上，DS个体因氧化应激而造成的损害更大。目前的研究表明，运动训练也可以改善该人群的氧化应激。尽管了解的程度较差，但由于运动参与，DS个体有可能改善运动学习。本文提供了简短的评论，讨论了有关DS个体如何应对运动的最新研究。此外，建立了联系，提倡钝化的急性反应可能导致人们对运动困难的认识提高，进而增加了久坐的生活方式的可能性。尚未发现不良反应，并且没有反对运动参与的理论论据，因此得出结论，应该为DS患者实施适应性运动计划，以改善健康和生活质量。

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