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首页> 外文期刊>International Journal of Environmental Research and Public Health >Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis
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Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis

机译：轮班工作，包括工厂的夜间工作和长时间工作，增加了动脉粥样硬化的风险

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There is an abundance of literature reporting an association between shift work and cardiovascular disease (CVD). Few studies have examined early manifestation of CVD using advanced modern methodology. We established a group of 65 shift workers and 29 day workers (controls) in two industrial plants. For the shift workers, the shift schedule includes rotating shifts with day, evening and nightshifts, some day and nightshifts lasting for 12 h. The current paper describes cross-sectional data in a study running for three years. We collected background data by questionnaire and measured blood pressure, heart rate, lipids, glycosylated hemoglobin (HbA1c) and C-reactive protein (CRP). We examined arterial stiffness (central blood pressure, augmentation pressure and index, and pulse wave velocity) by the use of SphygmoCor ? (AtCor Medical Pty Ltd, Sydney, Australia) and the carotid arteries by ultrasound. We assessed VO 2max by bicycle ergometry. We applied linear and logistic regression to evaluate associations between total number of years in shift work and cardiovascular outcome measures. The day workers were older and had more pronounced arterial stiffness compared to the shift workers. Number of years as a shift worker was associated with increased carotid intima media thickness (max IMT) (B = 0.015, p = 0.009) and an elevated CRP (B = 0.06, p = 0.03). Within the normal range for this age group, VO 2max was 41 (9) ml/kg/min. Rotating shift work including day and night shifts lasting up to 12 h and evening shifts are associated with CVD-risk factors. This could imply an increased risk for coronary heart disease and stroke among these workers. Therefore, preventive measures should be considered for these groups of workers in order to prevent such diseases.
机译：有大量文献报道轮班工作与心血管疾病（CVD）之间存在关联。很少有研究使用先进的现代方法研究CVD的早期表现。我们在两个工厂建立了由65名轮班工人和29名日工（控件）组成的小组。对于轮班工人，轮班时间表包括轮班，包括白天，晚上和夜班，某些白天和夜班持续12小时。本论文描述了一项为期三年的研究中的横截面数据。我们通过问卷调查收集了背景数据，并测量了血压，心率，脂质，糖基化血红蛋白（HbA1c）和C反应蛋白（CRP）。我们通过使用SphygmoCor®检查了动脉僵硬度（中央血压，增强压力和指数以及脉搏波速度）。 （澳大利亚悉尼的AtCor Medical Pty Ltd）和通过超声检查的颈动脉。我们通过自行车测功法评估了VO 2max。我们应用线性和逻辑回归分析来评估轮班工作总年数与心血管结局指标之间的关联。与轮班工人相比，当日工人年龄更大，动脉僵硬程度更明显。轮班工人的年数与颈动脉内膜中层厚度（最大IMT）增加（B = 0.015，p = 0.009）和CRP升高（B = 0.06，p = 0.03）相关。在该年龄组的正常范围内，VO 2max为41（9）ml / kg / min。轮班工作包括白天和夜班，持续长达12小时，而夜班与CVD风险因素有关。这可能意味着这些工人罹患冠心病和中风的风险增加。因此，应考虑对这些工人群体采取预防措施，以预防此类疾病。

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