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首页> 外文期刊>International Journal of Environmental Research and Public Health >Exposures of 129 Preschool Children to Organochlorines, Organophosphates, Pyrethroids, and Acid Herbicides at Their Homes and Daycares in North Carolina
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Exposures of 129 Preschool Children to Organochlorines, Organophosphates, Pyrethroids, and Acid Herbicides at Their Homes and Daycares in North Carolina

机译：北卡罗来纳州的129名学龄前儿童在家中和日托中接触有机氯，有机磷酸盐，拟除虫菊酯和酸性除草剂

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Few data exist on the concurrent exposures of young children to past-use and current-use pesticides in their everyday environments. In this further analysis of study data, we quantified the potential exposures and intake doses of 129 preschool children, ages 20 to 66 months, to 16 pesticides (eight organochlorines, two organophosphates, three pyrethroids, and three acid herbicides). Environmental samples (soil, dust, outdoor air, and indoor air) and personal samples (hand wipes, solid food, and liquid food) were collected at 129 homes and 13 daycare centers in six counties in North Carolina between 2000 and 2001. α-Chlordane, γ-chlordane, heptachlor, chlorpyrifos, diazinon, cis-permethrin, trans-permethrin, and 2,4-dichlorophenoxyacetic acid (2,4-D) were detected ≥50% in two or more media in both settings. Of these pesticides, the children’s estimated median potential intake doses through dietary ingestion, nondietary ingestion, and inhalation routes were the highest for 2,4-D and cis/trans-permethrin (both 4.84 ng/kg/day), cis/trans-permethrin (2.39 ng/kg/day), and heptachlor (1.71 ng/kg/day), respectively. The children’s estimated median potential aggregate intake doses by all three routes were quantifiable for chlorpyrifos (4.6 ng/kg/day), cis/trans-permethrin (12.5 ng/kg/day), and 2,4-D (4.9 ng/kg/day). In conclusion, these children were likely exposed daily to several pesticides from several sources and routes at their homes and daycares.
机译：很少有关于幼儿在日常环境中同时暴露于过去使用和当前使用的农药的数据。在对研究数据的进一步分析中，我们量化了129名年龄在20至66个月的学龄前儿童对16种农药（八种有机氯，两种有机磷酸盐，三种拟除虫菊酯和三种酸性除草剂）的潜在暴露量和摄入剂量。 2000年至2001年之间，在北卡罗来纳州的6个县的129所家庭和13个日托中心中收集了环境样品（土壤，灰尘，室外空气和室内空气）和个人样品（手巾，固体食品和液体食品）。α-在两种设置中的两种或更多种介质中，检出的氯丹，γ-氯丹，七氯，毒死rif，二嗪农，顺氯菊酯，反式氯菊酯和2,4-二氯苯氧乙酸（2,4-D）≥50％。在这些农药中，儿童通过饮食摄入，非饮食摄入和吸入途径估计的中位潜在摄入剂量最高，是2,4-D和顺式/反-氯菊酯（均为4.84 ng / kg /天），顺式/反式-氯菊酯（2.39 ng / kg /天）和七氯（1.71 ng / kg /天）。通过毒死rif（4.6 ng / kg /天），顺式/反苄氯菊酯（12.5 ng / kg /天）和2,4-D（4.9 ng / kg），可通过这三种途径估计儿童的潜在潜在总摄入量的中位数/天）。总之，这些孩子很可能每天在家中和日托中接触来自多种来源和途径的多种农药。

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