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首页> 外文期刊>International Journal of Environmental Research and Public Health >Minireview: The Epigenetic Modulation of KISS1 in Reproduction and Cancer
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Minireview: The Epigenetic Modulation of KISS1 in Reproduction and Cancer

机译:Minireview:KISS1在生殖和癌症中的表观遗传调控

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Epigenetics describes how both lifestyle and environment may affect human health through the modulation of genome functions and without any change to the DNA nucleotide sequence. The discovery of several epigenetic mechanisms and the possibility to deliver epigenetic marks in cells, gametes, and biological fluids has opened up new perspectives in the prevention, diagnosis, and treatment of human diseases. In this respect, the depth of knowledge of epigenetic mechanisms is fundamental to preserving health status and to developing targeted interventions. In this minireview, we summarize the epigenetic modulation of the KISS1 gene in order to provide an example of epigenetic regulation in health and disease.
机译:表观遗传学描述了生活方式和环境如何通过调节基因组功能而不改变DNA核苷酸序列如何影响人类健康。几种表观遗传机制的发现以及在细胞,配子和生物体液中传递表观遗传标记的可能性,为预防,诊断和治疗人类疾病开辟了新的前景。在这方面,对表观遗传机制的深入了解对于保持健康状况和制定有针对性的干预措施至关重要。在此小型审查中,我们总结了KISS1基因的表观遗传调控,以便为健康和疾病中的表观遗传调控提供示例。

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