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Sensitivity and specificity of median nerve ultrasonography in diagnosis of carpal tunnel syndrome

机译:正中神经超声检查对腕管综合征的敏感性和特异性

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Background: Although controversial, recent studies have demonstrated advantages of sonographic techniques in the diagnosis of carpal tunnel syndrome (CTS). The purpose of this study was to assess the utility of median nerve ultrasonography in the diagnosis of CTS in Iranian patients.Methods: Ninety patents with clinically suspected CTS were studied. Based on gold standard electromyographyerve conduction velocity studies, wrists with CTS were divided into three groups on the basis of severity of CTS, ie, mild, moderate, and severe. In addition, both sides of the wrist were examined using sonography. Transverse images of the median nerve were obtained and median nerve cross-section areas were measured at three levels, ie, immediately proximal to the carpal tunnel inlet, at the carpal tunnel inlet, and at the carpal tunnel outlet. Furthermore, flexor retinaculum thickness was evaluated.Results: The mean age of the studied patients was 48.52 ± 12.17 years. Median values of the median nerve cross-section at the carpal tunnel inlet, carpal tunnel outlet, and proximal carpal tunnel significantly differed between the wrists with and without CTS (P < 0.05). Comparisons between the CTS groups (mild, moderate, and severe) and non-CTS wrists demonstrated that the median cross-sections of median nerve at the carpal tunnel inlet, carpal tunnel outlet, and inlet proximal carpal tunnel were significantly greater in the severe CTS group than in the other three groups (P < 0.05). The results showed that the median nerve cross-section at the three levels of carpal tunnel could only fairly differentiate severe CTS from other cases.Conclusion: The present study demonstrated that median nerve ultrasonography cannot replace the gold standard test (nerve conduction velocity) for the diagnosis of CTS because of low overall sensitivity and specificity, although it might provide useful information in some patients.
机译:背景:尽管存在争议,但最近的研究证明了超声检查技术在腕管综合症(CTS)诊断中的优势。这项研究的目的是评估正中神经超声检查在伊朗患者CTS诊断中的实用性。方法:研究了90项临床可疑CTS专利。根据金标准肌电图/神经传导速度研究,根据CTS的严重程度,轻度,中度和重度,将具有CTS的手腕分为三组。另外,使用超声检查检查了手腕的两侧。获得正中神经的横断面图像,并在三个水平(即,腕管入口的近端,腕管入口和腕管出口)测量正中神经横截面积。结果:研究患者的平均年龄为48.52±12.17岁。在有和没有CTS的手腕之间,腕管入口,腕管出口和腕管近端的中位神经横截面中值存在显着差异(P <0.05)。 CTS组(轻度,中度和重度)与非CTS手腕之间的比较表明,在严重CTS中,腕管入口,腕管出口和腕管近端入口的正中神经横截面中值明显更大组比其他三组(P <0.05)。结果表明,腕管三个层面的正中神经横断面只能将严重的CTS与其他病例区分开。结论:本研究表明,正中神经超声检查不能替代金标准测试(神经传导速度)。尽管CTS在某些患者中可能提供有用的信息,但由于其总体敏感性和特异性较低,因此可以进行CTS诊断。

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