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首页> 外文期刊>International Journal of General Medicine >Treatment patterns associated with stroke prevention in patients with atrial fibrillation in three major cities in the People’s Republic of China
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Treatment patterns associated with stroke prevention in patients with atrial fibrillation in three major cities in the People’s Republic of China

机译：中华人民共和国三大城市房颤患者卒中预防相关的治疗方式

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Background: Atrial fibrillation (AF) is associated with an increased risk of stroke. This study assessed treatment patterns associated with stroke prevention among patients with AF in three major cities of the People’s Republic of China.Methods: A random sample of 2,862 medical charts for patients with AF at six tertiary hospitals located in Beijing, Shanghai, and Guangzhou between 2003 and 2008 were reviewed. Patient demographics, clinical characteristics, and treatment patterns were extracted from medical charts. Antithrombotic regimens included antiplatelets, anticoagulants, and a combination of both. Descriptive analyses were performed to summarize basic antithrombotic patterns. A logistic regression model examined demographic and clinical factors associated with antithrombotic treatment patterns.Results: Of the patient sample, 55% were male, the average age was 72 years (49% ≥75 years), 15% had valvular AF, 78% had nonvalvular AF, and the remainder had unspecified AF. CHADS2 scores ≥2 were reported for 53% of patients. Antithrombotic treatment was not received by 17% of patients during hospitalization, and 66% did not receive warfarin. Among patients with valvular or nonvalvular AF, 33%, 30%, and 20% received antiplatelet, anticoagulation, and antiplatelet plus anticoagulation treatments, respectively. For patients with CHADS2 scores of 0, 1, 2, 3, and ≥4, 52%, 42%, 28%, 21%, and 21%, respectively, were treated with warfarin. Predictors of no antithrombotic treatment included age and hospital location.Conclusion: Anticoagulation therapy was underused in Chinese patients with AF. Antithrombotic treatment was not associated with stroke risk. Further studies need to examine the clinical consequences of various antithrombotic treatment patterns in Chinese patients with AF.
机译：背景：房颤（AF）与中风的风险增加相关。这项研究评估了中国三个主要城市的房颤患者中风预防相关的治疗方式。方法：在北京，上海和广州之间的六家三级医院之间随机抽取2862张房颤病历回顾了2003年和2008年。从医学图表中提取了患者的人口统计学，临床特征和治疗方式。抗血栓形成方案包括抗血小板，抗凝剂和两者的组合。进行描述性分析以总结基本的抗血栓形成模式。 Logistic回归模型检查了与抗栓治疗模式相关的人口统计学和临床​​因素。结果：患者样本中，男性占55％，平均年龄为72岁（49％≥75岁），心脏瓣膜房颤为15％，心脏瓣膜房颤为78％。非瓣膜性房颤，其余者未明确房颤。据报道53％的患者CHADS2评分≥2。住院期间17％的患者未接受抗血栓治疗，而66％的患者未接受华法林治疗。在患有瓣膜性或非瓣膜性AF的患者中，分别有33％，30％和20％接受抗血小板，抗凝和抗血小板加抗凝治疗。对于CHADS2评分分别为0、1、2、3和≥4的患者，分别用华法林治疗了52％，42％，28％，21％和21％。没有抗血栓治疗的预测因素包括年龄和住院地点。结论：中国房颤患者未充分使用抗凝治疗。抗血栓治疗与中风风险无关。进一步的研究需要检查各种抗血栓治疗模式对中国房颤患者的临床后果。

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