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首页> 外文期刊>International Journal of General Medicine >Utility of the heated lidocaine/tetracaine patch in the treatment of pain associated with shoulder impingement syndrome: a pilot study
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Utility of the heated lidocaine/tetracaine patch in the treatment of pain associated with shoulder impingement syndrome: a pilot study

机译：加热的利多卡因/丁卡因贴剂在治疗肩部撞击综合征相关疼痛中的实用性：一项初步研究

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Introduction: Pain control is an important first step in the treatment of shoulder impingement syndrome (SIS) because fear of pain must be removed as an obstacle to participation in an appropriate physical therapy program.Methods: Adult patients with SIS-associated pain of at least 2 weeks’ duration and who had an average pain score of ≥4 on the zero- to ten-point Numeric Pain Rating Scale were eligible to enroll in this 2-week pilot study. Patients were treated with the heated lidocaine/tetracaine (70 mg/70 mg) patch (HLT patch) placed over the site of shoulder tenderness each morning and evening for a period of 2 to 4 hours. Average and worst pain during the previous 24 hours and shoulder range of motion were assessed at baseline and on Day 14. Results were expressed as change and percent change from baseline to Day 14. This pilot study was not powered for rigorous statistical analysis.Results: Twenty patients (seven male, 13 female; average age 51.2 ± 10.8 years [mean ± standard deviation]) enrolled in this study, and 18 patients completed the protocol. The mean average pain score at baseline was 5.5 ± 1.1 (range 4 to 8). In the per-protocol population, average and worst pain scores declined by 2.4 ± 2.0 and 3.7 ± 2.7 points, respectively. Two-thirds of the patients demonstrated a clinically meaningful ≥30% decline in average pain score, and half of the patients demonstrated a ≥50% decline in average pain score. Shoulder internal rotation increased by 29.7° ± 21.8° and abduction increased by 40.0° ± 44.2°. Application-site erythema was reported by ten patients at some time during the study.Conclusion: Patients treated with the HLT patch for 14 days demonstrated clinically meaningful improvement in pain intensity and range of motion. Further controlled research is necessary to characterize the efficacy and tolerability of the HLT patch in the treatment of SIS.
机译：简介：疼痛控制是治疗肩膀撞击综合征（SIS）的重要的第一步，因为必须消除对疼痛的恐惧，这是参加适当的物理治疗计划的障碍。方法：患有SIS相关疼痛的成年患者至少持续时间为2周且在0到10点数字疼痛评分量表上的平均疼痛评分≥4的患者有资格参加这项为期2周的试验研究。每天早晨和晚上，用加热的利多卡因/丁卡因（70毫克/ 70毫克）贴剂（HLT贴剂）治疗患者肩痛部位2至4个小时。在基线和第14天评估了前24小时的平均疼痛和最严重疼痛以及肩部运动的范围。结果表示为从基线到第14天的变化和变化百分比。该试验研究无力进行严格的统计分析。结果：该研究纳入了20名患者（男7例，女13例;平均年龄51.2±10.8岁[平均±标准差]），其中18例患者完成了研究方案。基线时的平均平均疼痛评分为5.5±1.1（范围为4到8）。在按协议分类的人群中，平均和最差的疼痛评分分别下降了2.4±2.0和3.7±2.7点。三分之二的患者表现出临床意义上的平均疼痛评分下降≥30％，一半的患者表现出的平均疼痛评分下降≥50％。肩部内旋转增加29.7°±21.8°，外展增加40.0°±44.2°。在研究期间的某个时间，有十名患者报告了应用部位红斑。结论：HLT贴片治疗14天的患者在疼痛强度和运动范围方面表现出临床上有意义的改善。必须进行进一步的对照研究才能鉴定HLT贴剂在SIS治疗中的功效和耐受性。

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