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首页> 外文期刊>International journal of hyperthermia: The official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group >Contrast-enhanced ultrasound-guided microwave ablation for hepatocellular carcinoma inconspicuous on conventional ultrasound
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Contrast-enhanced ultrasound-guided microwave ablation for hepatocellular carcinoma inconspicuous on conventional ultrasound

机译:超声引导下超声造影对肝细胞癌的影响

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Objective: To evaluate the efficiency and feasibility of contrast-enhanced ultrasound (CEUS)-guided microwave ablation for hepatocellular carcinoma inconspicuous on conventional US. Materials and methods: From March 2006 to February 2010, 107 patients (93 male, 14 female; mean age 58.9?±?11.0 years) with 107 hepatocellular carcinoma (HCC) nodules (mean maximum diameter 19.5?±?8.5?mm) inconspicuous on conventional US underwent microwave (MW) ablation under CEUS guidance in this study. US contrast agent was SonoVue (Bracco, Milan, Italy), a second-generation contrast agent. CEUS was performed first, and then MW ablation was carried out by means of CEUS guidance under unconscious intravenous anaesthesia if the tumours were displayed on CEUS. Results: 105 tumours were successfully visualised on CEUS by using 1–2 times contrast agent injection and MW ablation was performed under CEUS guidance. The technical success rate was 98.13% (105/107). The number of antenna insertions for each tumour was 1.89?±?0.92, and the mean session of MW ablation for each tumour was 1.08?±?0.28. The mean duration of energy application for each tumour was 7.05?±?4.03?min. The follow-up time was 12–54 months (median 18 months). The technique effectiveness rate was 99.05% (104/105). The local tumour progression rate was 1.9% (2/105). There were no severe complications in any patients. Conclusion: CEUS-guided MW ablation is an efficient and feasible treatment method for patients with hepatocellular carcinoma inconspicuous on conventional US.
机译:目的:评估超声造影(CEUS)引导的微波消融治疗常规美国不常见的肝细胞癌的效率和可行性。材料与方法:2006年3月至2010年2月,107例肝癌结节(平均最大直径19.5±8.5毫米)不明显(107例,男性93例,女性14例;平均年龄58.9±11.0岁)。在这项研究中,在CEUS的指导下,对常规美国常规微波消融术进行了研究。美国的造影剂是第二代造影剂SonoVue(位于意大利米兰的Bracco)。如果肿瘤显示在CEUS上,则首先进行CEUS,然后在无意识的静脉麻醉下通过CEUS指导进行MW消融。结果:通过使用1-2次造影剂注射在CEUS上成功可视化了105个肿瘤,并在CEUS的指导下进行了MW消融。技术成功率为98.13%(105/107)。每个肿瘤的触角插入数为1.89±±0.92,每个肿瘤的平均MW消融为1.08±±0.28。每个肿瘤的平均能量施加时间为7.05±±4.03μmin。随访时间为12–54个月(中位数为18个月)。技术有效率为99.05%(104/105)。局部肿瘤进展率为1.9%(2/105)。任何患者均无严重并发症。结论:CEUS引导的MW消融是一种对常规US不起眼的肝细胞癌患者的有效,可行的治疗方法。

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