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首页> 外文期刊>International Journal of Chronic Diseases >A Comparison of the Prevalence of the Metabolic Syndrome among Sri Lankan Patients with Type 2 Diabetes Mellitus Using WHO, NCEP-ATP III, and IDF Definitions
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A Comparison of the Prevalence of the Metabolic Syndrome among Sri Lankan Patients with Type 2 Diabetes Mellitus Using WHO, NCEP-ATP III, and IDF Definitions

机译：使用WHO，NCEP-ATP III和IDF定义比较斯里兰卡2型糖尿病患者代谢综合征的患病率

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Background. Presence of metabolic syndrome (MetS) in patients with type 2 diabetes mellitus (type 2 DM) increases the risk of cardiovascular morbidity and mortality. Therefore, recognition of MetS in type 2 DM is important in initiating the appropriate preventive and therapeutic measures. The commonly used definitions have similarities and discrepancies. Aims of this study was to investigate the prevalence of MetS among patients with type 2DM using all three well known (WHO, IDF, and NCEP-ATP III) definitions and to identify the concordance and the difference of these three definitions. Methods. This cross-sectional study included patients with type 2 DM who were followed up at the regional diabetes centre in Galle, Sri Lanka. A total of 2913 type 2 DM patients were recruited by convenient sampling method, and their clinical and biochemical data were collected. Results. The mean age (SD) of the sample was 49.9 (10.2) years and the mean duration of diabetes was 5.04 (5.71). Prevalence of MetS was highest by WHO (70%) followed by IDF (44%) and NCEP-ATP III (29%) definitions. The prevalence was significantly higher in women according to all three definitions, and the difference was most marked with NCEP-ATP III and IDF definitions. Around 25% were identified as having MetS by all three definitions whereas around 45% were recognized with MetS by two definitions. While concordances between WHO with IDF (0.37, p < 0.001) and NCEP-ATP III (0.24, p < 0.001) criteria were poor, they were average (0.53, p < 0.001) between NCEP-ATP III and IDF criteria. Conclusions. The prevalence of MetS among patients with type 2 DM can significantly be varied based on the definition used and the three definitions of MetS recognized different set of individuals. The highest prevalence of MetS was observed with WHO (70.6%) whereas lowest was observed with NCEP-ATP III definition.
机译：背景。 2型糖尿病（2型糖尿病）患者存在代谢综合征（MetS）会增加心血管疾病发病率和死亡率的风险。因此，在开始采取适当的预防和治疗措施中，识别2型DM中的MetS很重要。常用定义具有相似性和差异性。这项研究的目的是使用所有三个众所周知的（WHO，IDF和NCEP-ATP III）定义调查2DM型患者中MetS的患病率，并确定这三个定义的一致性和差异性。方法。这项横断面研究包括斯里兰卡加勒地区糖尿病中心的2型DM患者。共有2913例2型DM患者通过便利抽样方法招募，并收集了他们的临床和生化数据。结果。样本的平均年龄（SD）为49.9（10.2）岁，糖尿病的平均持续时间为5.04（5.71）。世卫组织（70％），随后的IDF（44％）和NCEP-ATP III（29％）定义的MetS患病率最高。根据所有三个定义，女性的患病率明显更高，并且差异最大的是NCEP-ATP III和IDF定义。通过这三个定义，大约25％的人被确认患有MetS，而通过两个定义，大约45％的人被确认具有MetS。尽管WHO与IDF（0.37，p <0.001）和NCEP-ATP III（0.24，p <0.001）标准之间的一致性差，但NCEP-ATP III与IDF标准之间的平均值相差（0.53，p <0.001）。结论。 MetS在2型DM患者中的患病率可以根据使用的定义而有显着差异，并且MetS的三个定义可以识别不同的个体。世卫组织发现MetS的患病率最高（70.6％），而NCEP-ATP III定义的患病率最低。

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