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Prevention and management of infection associated with transrectal ultrasound guided prostate biopsy in Ireland

机译:爱尔兰经直肠超声引导下前列腺穿刺活检相关感染的预防和管理

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The incidence of transrectal ultrasound (TRUS)–guided prostate biopsy associated infection is reportedly increasing, particularly antimicrobial resistant (AMR) infections. To inform development of an inaugural national policy on prevention and management of infection post TRUS biopsy, we conducted a national survey of ten prostate cancer centres that perform approximately 90% of public prostate biopsies in Ireland. An on-line questionnaire regarding prostate biopsy pathways, pre-biopsy AMR risk assessment and antimicrobial prophylaxis regimens, and post-biopsy infection surveillance and management was circulated to all centres. Data from 1st January 2011 to 30th June 2013 were collected retrospectively from July to September 2013. Data were analysed using Microsoft Excel? software. The results of this survey demonstrated marked variation of practices nationally. Three centres reported risk assessing for AMR colonisation pre-biopsy. AMR screening was not conducted routinely in any centre. Antimicrobial prophylaxis regimens, surveillance programmes and empiric therapy guidelines for sepsis also varied between centres. A range of infectious complications were reported, both bloodstream infection (BSI) and non-BSI, however, due to use of non-standardised case definitions, national infection rates could not be generated. At the time of the survey, there were no Irish guidelines and centres followed American and/or European guidelines. Following our survey the National Cancer Control Programme published a “National Policy on the Prevention and Management of Infection post Transrectal Ultrasound-guided Prostate Biopsy” in June 2014 to assist in standardising practice and reducing risk of infectious complications.
机译:据报道,经直肠超声(TRUS)引导的前列腺活检相关感染的发生率正在增加,尤其是抗微生物耐药性(AMR)感染。为了为制定TRUS活检后感染的预防和管理国家政策的制定提供信息,我们对十个前列腺癌中心进行了全国性调查,这些中心在爱尔兰进行了大约90%的公共前列腺活检。关于前列腺活检途径,活检前AMR风险评估和抗菌预防方案以及活检后感染监测和管理的在线调查表已分发给所有中心。回顾性收集2011年7月至2013年9月的2011年1月1日至2013年6月30日的数据。使用Microsoft Excel分析数据。软件。这项调查的结果表明,全国范围内的做法差异很大。三个中心报告了对AMR定植活检前的风险评估。没有在任何中心进行AMR筛查。各中心之间的脓毒症抗菌药物预防方案,监测方案和经验性治疗指南也有所不同。报告了一系列感染并发症,包括血流感染(BSI)和非BSI,但是,由于使用了非标准化的病例定义,因此无法产生全国感染率。在调查时,尚无爱尔兰准则,中心也遵循美国和/或欧洲准则。根据我们的调查,国家癌症控制计划于2014年6月发布了“预防和管理经直肠超声引导的前列腺穿刺活检后感染的国家政策”,以帮助规范操作并降低感染并发症的风险。

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