Summary Various disorders result in jaundice. Adrenal insufficiency is a rare cause of neonatal cholestasis, which is reversible with prompt glucocorticoid administration. Cholestasis caused by adrenal insufficiency has not been reported in adult patients. We present a case of a 65-year-old male with jaundice and without hepatitis A, B, or C. Endoscopic retrograde cholangiopancreatography showed a patent biliary tract. Liver pathology revealed no malignancy but showed bile stasis compatible with cholestatic hepatitis. The patient's jaundice persisted for 7 weeks, and at the same time, adrenal insufficiency was diagnosed. Adrenal insufficiency was recovered with glucocorticoid therapy, and the jaundice was cured.
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