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首页> 外文期刊>International Journal of Molecular Epidemiology and Genetics >The development of molecular epidemiology to elucidate cancer risk and prognosis: a historical perspective
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The development of molecular epidemiology to elucidate cancer risk and prognosis: a historical perspective

机译:分子流行病学的发展,以阐明癌症的风险和预后:历史的观点

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Molecular epidemiology in cancer research grew from the field of chemical carcinogenesis and the use biomarkers for environmental exposures, with incorporation of principles from early pharmacogenetics. Over the years, molecular epidemiology has become extremely complex, with studies evaluating associations between cancer risk and prognosis and numerous markers of susceptibility, exposure and early effects, as well as epidemiologic factors. In this article, we review the field of molecular epidemiology from a historical perspective, commenting on current status of the field and future directions.
机译:癌症研究中的分子流行病学源于化学致癌作用领域以及将生物标志物用于环境暴露的过程,并结合了早期药物遗传学的原理。多年来,分子流行病学变得极为复杂,研究评估了癌症风险与预后之间的关联以及许多易感性,暴露和早期影响的标记以及流行病学因素。在本文中,我们从历史的角度回顾了分子流行病学领域,并对该领域的现状和未来方向进行了评论。

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