• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Nephrology >Primary Nephrotic Syndrome in Adults as a Risk Factor for Pulmonary Embolism: An Up-to-Date Review of the Literature
【24h】

Primary Nephrotic Syndrome in Adults as a Risk Factor for Pulmonary Embolism: An Up-to-Date Review of the Literature

机译：成人原发性肾病综合征作为肺栓塞的危险因素：文献的最新审查。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Patients with nephrotic syndrome are at an increased risk for thrombotic events; deep venous thrombosis, renal vein thrombosis, and pulmonary embolism are quite common in patients with nephrotic syndrome. It is important to note that nephrotic syndrome secondary to membranous nephropathy may impose a greater thrombotic risk for unclear reasons. Increased platelet activation, enhanced red blood cell aggregation, and an imbalance between procoagulant and anticoagulant factors are thought to underlie the excessive thrombotic risk in patients with nephrotic syndrome. The current scientific literature suggests that patients with low serum albumin levels and membranous nephropathy may benefit from primary prophylactic anticoagulation. A thorough approach which includes accounting for all additional thrombotic risk factors is, therefore, essential. Patient counseling regarding the pros and cons of anticoagulation is of paramount importance. Future prospective randomized studies should address the question regarding the utility of primary thromboprophylaxis in patients with nephrotic syndrome.
机译：肾病综合征患者血栓形成的风险增加;肾病综合征患者深静脉血栓形成，肾静脉血栓形成和肺栓塞很常见。重要的是要注意，由于不清楚的原因，继发于膜性肾病的肾病综合征可能会带来更大的血栓风险。肾病综合征患者血小板活化增强，红细胞聚集增强以及促凝血因子和抗凝因子之间的失衡被认为是血栓形成风险过高的基础。当前的科学文献表明，血清白蛋白水平低和膜性肾病的患者可能会受益于原发性预防性抗凝治疗。因此，包括所有其他血栓形成危险因素在内的全面方法至关重要。关于抗凝治疗的利弊的患者咨询至关重要。未来的前瞻性随机研究应解决肾病综合征患者一级血栓预防的实用性问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号