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Noninflammatory disorders mimic juvenile idiopathic arthritis

机译:非炎性疾病模仿青少年特发性关节炎

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Juvenile idiopathic arthritis (JIA) is the most common chronic childhood arthritis; unfortunately, no diagnostic tool is available. Genetic disorders with musculoskeletal involvement that mimic chronic polyarthritis should be considered in the differential diagnostics of JIA. Normal inflammatory markers and characteristic radiological features are able to distinguish these disorders from JIA. Timely diagnosis of these disorders is crucial to offer the family proper genetic counseling and avoid inappropriate therapy. This review highlights selected noninflammatory disorders that often present with articular manifestations and that are often mislabeled as JIA. The focus is on the clinical, biochemical, and imaging features of these disorders.
机译:少年特发性关节炎(JIA)是最常见的慢性儿童期关节炎。不幸的是,没有可用的诊断工具。在JIA的鉴别诊断中,应考虑模仿慢性多发性关节炎的肌肉骨骼受累的遗传性疾病。正常的炎症标记和特征性放射学特征能够将这些疾病与JIA区别开来。及时诊断这些疾病对于为家庭提供适当的遗传咨询并避免不适当的治疗至关重要。这篇综述重点介绍了通常表现为关节表现且经常被错误标记为JIA的非炎性疾病。重点是这些疾病的临床,生化和影像学特征。

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