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首页> 外文期刊>International Journal of Poultry Sciences >Effect of Growth Selection on Adipogenic Gene Expression During the Development of the Turkey Breast Muscle
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Effect of Growth Selection on Adipogenic Gene Expression During the Development of the Turkey Breast Muscle

机译：生长选择对火鸡胸肌发育过程中成脂基因表达的影响

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The effect of growth selection in turkeys was studied for its effect on the expression of adipogenic genes in the pectoralis major (p. major) muscle both in vivo and in vitro in a random bred control line (RBC2) and a subline F selected long-term from the RBC2 for only increased 16-wk body weight. The expression of the adipogenic transcription factors peroxisome proliferator-activated receptor gamma (PPARγ), CCAAT/enhancer binding protein α (C/EBPα) and stearoyl-CoA desaturase (SCD) were measured in p. major muscle tissue isolated from 18 and 24 d old embryos and 1 and 16-wk old RBC2 and F line turkeys and in vitro with adult myoblasts (satellite cells) isolated from RBC2 and F line turkey p. major muscle tissue during proliferation and differentiation. Both in vivo and in vitro , the F line expressed significantly higher levels of PPARγ, C/EBPα and SCD. The data from the current study provides novel information about the effect of growth selection in turkeys on the potential of fat formation in vivo in the p. major muscle and the possible transdifferentiation of myogenic satellite cells to an adipogenic lineage.
机译：研究了生长选择在火鸡中的作用，在随机繁殖的对照系（RBC2）和F系中选择了长期从RBC2开始只增加了16周的体重。测量了成脂转录因子过氧化物酶体增殖物激活受体γ（PPARγ），CCAAT /增强子结合蛋白α（C /EBPα）和硬脂酰辅酶A去饱和酶（SCD）的表达。从18和24 d个老胚胎以及1和16周龄的RBC2和F系火鸡分离出的主要肌肉组织，并在体外与从RBC2和F系火鸡p分离的成年成肌细胞（卫星细胞）分离。主要肌肉组织在增殖和分化过程中。在体内和体外，F系均表达显着更高水平的PPARγ，C /EBPα和SCD。来自当前研究的数据提供了有关火鸡生长选择对鸡体内脂肪形成潜力的影响的新颖信息。主要肌肉以及成肌卫星细胞向成脂谱系的可能转分化。

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