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首页> 外文期刊>International Journal of Pharmacological Research >Prescribing pattern of antihypertensive in hypertensive patients with compelling indication
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Prescribing pattern of antihypertensive in hypertensive patients with compelling indication

机译：有明显适应症的高血压患者的降压处方模式

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Aim: The aim of the study is to assess the various prescribing patterns in hypertension and compiling indications with JNC 8 guidelines. Objective : To assess the prescribing pattern in hypertensive patients and to evaluate the rationality in regards to JNC-8 Guidelines in a tertiary care hospital. Methods : It was a prospective, observational study conducted for 3 months in 250 hypertensive prescriptions with comorbidities who get admitted in the hospital were screened for the study. The data collected from the participants was entered into Microsoft excel spreadsheet. Results : A total of 250 hypertensive patients with different comorbidities were included in which 140 males and 110 females. The most commonly reported first three co-morbidities along with hypertension were diabetes mellitus 139 (55.6%), and coronary artery disease 48 (19.2%). Monotherapy was given in almost 166 (66.4%) patients and dual drug therapy was indicated in 52 (20.8%) patients, triple therapy was used only in 7 (2.8%) patients in the total sample size. Quadruple therapy is not preferred combination therapy which accounts only in 25(10%) patients. Conclusion: We conclude that calcium channel blockers and angiotensin II receptor blockers were the most frequently prescribed class of drugs; moreover single or in combination with other class of drugs for effective control of blood pressure patients with different compelling indications. Monotherapy was preferred than combination therapy.
机译：目的：该研究的目的是评估高血压的各种处方方式，并根据JNC 8指南编制适应症。目的：评估三级医院高血压患者的处方方式，并评估有关《 JNC-8指南》的合理性。方法：这是一项针对前瞻性观察性研究，共筛选了250例合并医院的合并症的高血压处方，进行了为期3个月的筛选。从参与者收集的数据已输入到Microsoft excel电子表格中。结果：共纳入250例不同合并症的高血压患者，其中男性140例，女性110例。高血压最常见的前三种合并症是糖尿病139（55.6％）和冠心病48（19.2％）。在总样本量中，将近166（66.4％）位患者进行了单药治疗，而在52位（20.8％）患者中进行了双重药物治疗，仅在7位（2.8％）患者中使用了三药治疗。四联疗法不是仅占25（10％）患者的首选联合疗法。结论：我们得出结论，钙通道阻滞剂和血管紧张素II受体阻滞剂是最常用的处方药。此外，可以单独或与其他类别的药物联合使用，以有效控制具有不同强迫症的血压患者。单药治疗优于联合治疗。

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