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首页> 外文期刊>International Journal of Preventive Medicine >Effects of Physical Activity on Risk of Colorectal Cancer: A Case–control Study
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Effects of Physical Activity on Risk of Colorectal Cancer: A Case–control Study

机译：体育锻炼对结直肠癌风险的影响：病例对照研究

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Background: The prevalence of colorectal cancer (CRC) is rapidly increasing in Iran. It holds the most prevalent cancer after skin, breast, and gastric cancers among the Iranian population. The current study was designed to investigate the effects of leisure time, occupational and household physical activity as well as exercise on the risk of CRC in the Iranian population. Methods: In this population-based case–control study, 100 individuals with a recent diagnosis of CRC who were eligible for the study were recruited between 2006 and 2008. The control groups were selected from patients’ companions (excluding first- and second-degree relatives) without past history of cancer or any physical disability. Physical activity of the participants was evaluated using a Kriska retrospective physical activity questionnaire. The relation between CRC and physical activity was assessed via logistic regression model and calculating the odds ratio (OR) as well as a confidence interval (CI) of 95%. Results: According to the findings, the adjusted OR of occupational (OR = 0.98, 95%, CI: 0.95–1.02) and house holding physical activities (OR = 1.03, 95% CI: 0.99–1.08) were not significantly different between the case and control groups for women ( P 0.05). The risk of CRC shows a significant reduction in individuals with moderate leisure physical activities compared to those with minimal activities (OR = 0.82, CI 95%: 0.73–0.98). Conclusions: The study suggests that the risk of CRC will decrease in individuals with higher leisure physical activities (especially with an increase in hours of brisk walking during the day).
机译：背景：在伊朗，结直肠癌（CRC）的患病率迅速上升。它是伊朗人群中仅次于皮肤癌，乳腺癌和胃癌的最普遍的癌症。当前的研究旨在调查休闲时间，职业和家庭体育活动以及运动对伊朗人口患CRC风险的影响。方法：在这项基于人群的病例对照研究中，从2006年至2008年之间招募了100名最近被诊断患有CRC并符合研究条件的个体。对照组选自患者的同伴（不包括一等和二等）。亲戚），没有癌症或任何身体残疾的既往史。使用Kriska回顾性体育锻炼问卷评估了参与者的体育锻炼。通过logistic回归模型并计算比值比（OR）以及95％的置信区间（CI）来评估CRC与身体活动之间的关系。结果：根据调查结果，职业之间的调整后OR（OR = 0.98，95％，CI：0.95–1.02）和家庭体育锻炼（OR = 1.03，95％CI：0.99–1.08）之间无显着差异。女性病例和对照组（P> 0.05）。与很少活动的人相比，进行中度休闲运动的人患CRC的风险显着降低（OR = 0.82，CI 95％：0.73-0.98）。结论：该研究表明，休闲运动较多的人（尤其是白天轻快行走时间增加）会降低CRC的风险。

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