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Estimation and Comparison of Levels of Salivary Nitric Oxide in Patients with Oral Lichen Planus and Controls

机译:口腔扁平苔藓患者和对照患者唾液中一氧化氮水平的估算和比较

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Background: Normal salivary function is considered to be critical for the maintenance of healthy oral mucosa. Oral fluids provide an easily available, non-invasive medium for the diagnosis of wide range of diseases and clinical situations. The objective of this study was to estimate and compare salivary nitric oxide levels in patients with oral lichen planus and healthy individuals. Methods: Saliva was collected by spitting method. Unstimulated whole saliva thus collected was refrigerated at 4°C, and processed within 24 h for the estimation of nitric oxide levels which was done using Griess reaction. The results were analyzed using Student's “ t ” test. Results: There was statistically significant difference in the levels of salivary nitric oxide between the study and control groups. Conclusions: The present study clearly indicates a significant increase in salivary nitric oxide levels in oral lichen planus patients as compared to controls.
机译:背景:正常的唾液功能被认为对维持健康的口腔粘膜至关重要。口服液为诊断多种疾病和临床状况提供了一种容易获得的非侵入性介质。这项研究的目的是评估和比较口腔扁平苔藓患者和健康个体唾液中一氧化氮的水平。方法:唾液收集方法为唾液收集。将由此收集的未刺激的整个唾液在4°C冷藏,并在24小时内处理以估算一氧化氮水平,这是使用Griess反应完成的。使用学生的“ t”检验分析结果。结果:研究组和对照组之间唾液中一氧化氮水平存在统计学差异。结论:本研究清楚地表明,与对照组相比,口腔扁平苔藓患者唾液中一氧化氮水平显着增加。

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