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首页> 外文期刊>International Journal of Preventive Medicine >Restless Legs Syndrome in Iranian Multiple Sclerosis Patients: A Case-Control Study
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Restless Legs Syndrome in Iranian Multiple Sclerosis Patients: A Case-Control Study

机译：伊朗多发性硬化症患者的不安腿综合征：病例对照研究

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Background: Restless legs syndrome (RLS) is a common movement disorder. The occurrence of this syndrome is due to genetic factors and lifestyle. This study performed to determine restless legs syndrome (RLS) prevalence in Iranian multiple sclerosis (MS) patients and the possible risk factors. Methods: This cross-sectional study was conducted with MS patients, and the age- and sex-matched control group comprised healthy persons. Then, all subjects were asked about RLS symptoms. After the diagnosis of RLS, the patients were divided into two groups: With and without RLS. In both groups, the following variables were evaluated: Age, sex, other underlying disease, duration of MS, MS course, family history of RLS, history of anemia, and drug intakes. The severity of the disease in subjects diagnosed with RLS was also evaluated. Results: A total of 126 patients in the MS group and 126 healthy controls were included in the study, with no statistically significant differences between them in terms of age and gender. In MS group, 82 (65.1%) and, in control group, 16 (12.7%) had RLS. The frequency of RLS in the MS patients was significantly higher than that in the control group. Among MS patients, 60 male (73.2%) and 22 female (26.8%) had RLS. Mean age of MS patients with RLS was significantly higher than that in MS patients without RLS. MS patients and higher EDSS score had more RLS symptoms. Conclusions: We suggest that RLS always be considered during neurological examinations of MS patients.
机译：背景：不安腿综合症（RLS）是一种常见的运动障碍。该综合征的发生是由于遗传因素和生活方式。这项研究旨在确定伊朗多发性硬化症（MS）患者的不安腿综合征（RLS）患病率和可能的危险因素。方法：这项横断面研究是针对MS患者进行的，年龄和性别匹配的对照组包括健康人。然后，向所有受试者询问RLS症状。诊断为RLS后，将患者分为两组：有和没有RLS。两组均评估以下变量：年龄，性别，其他潜在疾病，MS病程，MS病程，RLS家族史，贫血病史和药物摄入。还评估了诊断为RLS的受试者的疾病严重程度。结果：该研究共纳入MS组126例患者和126名健康对照者，年龄和性别之间无统计学差异。在MS组中，有RLS的有82例（65.1％），在对照组中有16例（12.7％）。 MS患者的RLS频率明显高于对照组。在MS患者中，RLS为男性60例（73.2％），女性22例（26.8％）。有RLS的MS患者的平均年龄显着高于无RLS的MS患者。 MS患者和较高的EDSS评分具有更多的RLS症状。结论：我们建议在MS患者的神经系统检查中始终考虑使用RLS。

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