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首页> 外文期刊>International Journal of Preventive Medicine >FIRST REPORT ON THE LIPID PROFILE LATE AFTER KAWASAKI DISEASE IN IRANIAN CHILDREN
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FIRST REPORT ON THE LIPID PROFILE LATE AFTER KAWASAKI DISEASE IN IRANIAN CHILDREN

机译：川崎病患后脂质谱的首次报道

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Background: Concerns have been raised about the possibility of a predisposition of Kawasaki disease (KD) to abnormal lipid profile after an acute phase of disease, which can predispose them to premature atherosclerosis later in life. We determined the lipid profile of children late after KD, and compared it with controls.Methods: This historical cohort was conducted on 32 subjects: 16 children with history of uncomplicated KD (age 11.8 ± 3.3 years, interval from the initial episode 7.1 years), and 16 healthy age-matched of their sibling or cousins. Fasting serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) levels were compared between groups. In addition, blood pressure and body mass index (BMI) were measured and compared.Results: Six out of 16 KD patients and 7 out of 16 controls had abnormal lipid values. No significant difference was found in mean values of systolic blood pressures, diastolic blood pressures, BMI, TG, TC, HDL-C, and LDL-C between cases and controls.Conclusions: We conclude that although Iranian KD children probably had no different lipid profile compared with controls, but due to finding dyslipidemia in more than one-third of KD subjects, we suggest that periodic control of lipid values in these patients is of crucial importance.
机译：背景：人们已经担心川崎病（KD）在疾病的急性期后易患异常脂质，这可能使他们在生命的晚些时候过早地患上动脉粥样硬化。我们确定了KD晚期儿童的血脂状况，并将其与对照组进行比较。方法：这项历史性队列研究针对32位受试者进行了研究：16名无KD病史的儿童（年龄11.8±3.3岁，初发间隔为7.1岁） ，以及16个年龄相匹配的健康兄弟姐妹或堂兄弟姐妹。比较两组之间的空腹血清总胆固醇（TC），高密度脂蛋白胆固醇（HDL-C），低密度脂蛋白胆固醇（LDL-C）和甘油三酸酯（TG）水平。结果：16例KD患者中有6例和16例对照组中有7例血脂异常。病例和对照组之间的收缩压，舒张压，BMI，TG，TC，HDL-C和LDL-C平均值均无显着差异。与对照组比较，但由于在超过三分之一的KD受试者中发现血脂异常，我们建议定期控制这些患者的血脂值至关重要。

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