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首页> 外文期刊>Infectious diseases in obstetrics and gynecology >Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women
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Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women

机译：将性传播感染的护理台诊断测试纳入艾滋病毒感染孕妇的南非产前保健计划的可接受性和可行性

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Background. Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) infections may increase the risk of vertical transmission of the human immunodeficiency virus (HIV). In resource-limited settings, symptomatic screening, and syndromic management of sexually transmitted infections (STIs) during pregnancy continue to be the standard of care. In the absence of diagnostic testing, asymptomatic infections in pregnant women go untreated. Objective. To describe the acceptability and feasibility of integrating diagnostic STI screening into first antenatal care visits for HIV-infected pregnant women. Methods. HIV-infected pregnant women were recruited during their first antenatal care visit from three antenatal care clinics in Tshwane District, South Africa, between June 2016 and October 2017. Self-collected vaginal swabs were used to screen for CT, NG, and TV with a diagnostic point-of-care (POC) nucleic acid amplification test. Those with STIs were provided treatment per South African national guidelines. Results. Of 442 eligible women, 430 (97.3%) agreed to participate and were tested. Of those with a positive STI test result ( = 173; 40.2%), 159 (91.9%) received same-day results and treatment; 100% of STI-infected women were treated within seven days. Conclusions. Integration of POC diagnostic STI screening into first-visit antenatal care services was feasible and highly acceptable for HIV-infected pregnant women.
机译：背景。沙眼衣原体（CT），淋病奈瑟氏菌（NG）和阴道滴虫（TV）感染可能会增加人类免疫缺陷病毒（HIV）垂直传播的风险。在资源有限的情况下，症状筛查和妊娠期间性传播感染（STIs）的综合管理仍然是护理的标准。在没有诊断测试的情况下，孕妇的无症状感染得不到治疗。目的。描述将艾滋病毒感染孕妇的首次性传播感染性STI筛查纳入首次产前检查的可接受性和可行性。方法。在2016年6月至2017年10月之间，从南非Tshwane区的三家产前保健诊所招募了接受HIV感染的孕妇，进行首次产前保健。我们使用自行收集的阴道拭子对CT，NG和TV进行筛查。诊断即时诊断（POC）核酸扩增测试。根据南非国家准则为患有性传播感染的人提供了治疗。结果。在442名合格妇女中，有430名（97.3％）同意参加测试。 STI测试结果阳性的患者（= 173; 40.2％），有159人（91.9％）获得了当天的结果和治疗。在7天内对100％的STI感染妇女进行了治疗。结论。将POC诊断性STI筛查纳入首次就诊产前保健服务是可行的，并且对于HIV感染的孕妇是高度可接受的。

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