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首页> 外文期刊>Infectious diseases in obstetrics and gynecology >Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women
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Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women

机译：将性传播感染的关注点诊断测试整合到艾滋病毒感染妇女的南非产前护理计划中的可接受性和可行性

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Background. Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) infections may increase the risk of vertical transmission of the human immunodeficiency virus (HIV). In resource-limited settings, symptomatic screening, and syndromic management of sexually transmitted infections (STIs) during pregnancy continue to be the standard of care. In the absence of diagnostic testing, asymptomatic infections in pregnant women go untreated. Objective. To describe the acceptability and feasibility of integrating diagnostic STI screening into first antenatal care visits for HIV-infected pregnant women. Methods. HIV-infected pregnant women were recruited during their first antenatal care visit from three antenatal care clinics in Tshwane District, South Africa, between June 2016 and October 2017. Self-collected vaginal swabs were used to screen for CT, NG, and TV with a diagnostic point-of-care (POC) nucleic acid amplification test. Those with STIs were provided treatment per South African national guidelines. Results. Of 442 eligible women, 430 (97.3%) agreed to participate and were tested. Of those with a positive STI test result ( n = 173; 40.2%), 159 (91.9%) received same-day results and treatment; 100% of STI-infected women were treated within seven days. Conclusions. Integration of POC diagnostic STI screening into first-visit antenatal care services was feasible and highly acceptable for HIV-infected pregnant women.
机译：背景。 Chlamydia Thachomatis（CT），Neisseria淋病（NG）和Trichomonas阴道（电视）感染可能会增加人类免疫缺陷病毒（HIV）垂直传播的风险。在资源限制的环境中，怀孕期间性传播感染（STIS）的对症筛查和综合征管理继续是护理标准。在没有诊断测试的情况下，孕妇中的无症状感染未经治疗。客观的。描述将诊断STI筛查集成为艾滋病毒感染妇女的第一次产前护理探查的可接受性和可行性。方法。在2016年6月和2017年之间，在Tshwane区的三个产前护理诊所招聘了艾滋病毒感染的孕妇。自收集的阴道拭子被用来筛选CT，NG和电视诊断治疗点（POC）核酸扩增试验。每南非国家指南提供STI的人。结果。 442个合格的妇女，430（97.3％）同意参加并进行测试。那些具有正STI测试结果的人（n = 173; 40.2％），159（91.9％）获得当天的结果和治疗; 100％的STI感染妇女在七天内进行治疗。结论。 PoC诊断STI筛选进入首次访问前提护理服务的整合是可行的，对艾滋病毒感染的孕妇可行而且非常可接受。

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