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首页> 外文期刊>International Journal of Research in Medical Sciences >Pulmonary functions in type 2 diabetes mellitus patients: an observational study at a tertiary level hospital in Mumbai, Maharashtra, India
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Pulmonary functions in type 2 diabetes mellitus patients: an observational study at a tertiary level hospital in Mumbai, Maharashtra, India

机译：2型糖尿病患者的肺功能：印度马哈拉施特拉邦孟买一家三级医院的观察性研究

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Background: Pulmonary complications of diabetes mellitus (DM) have been poorly characterized. A reduction in lung capacity has been reported previously in diabetics. We undertook a study to check the association between pulmonary function tests in type 2 DM. Also to determine their correlations with body mass index (BMI), glycemic control and other clinically evident complications like peripheral neuropathy. Methods: The study was conducted at tertiary care BYL Nair hospital, Mumbai where diabetic patients without any hypertension, cardiovascular disease, primary respiratory abnormalities and without any microangiopathic complications were enrolled. They were clinically evaluated for pulse, blood pressure, skin changes, BMI and various biochemical investigations. Blood sugar- fasting and post prandial, serum cholesterol, serum triglyceride, urinary proteins, electrocardiograph, X- ray chest were noted. Pulmonary function test was performed by spirometry. Peripheral neuropathy was looked for an association with pulmonary function tests (PFT). Results: Out of 200 patients 68% (136) patients had normal PFT, mild obstruction 10.0% (20), mild restriction 10% (20) moderate obstruction 2% (4), moderate restriction 4% (8) and mixed 6% (12) were noted. FEV1, FVC values were statistically significantly reduced in patients with peripheral neuropathy and FEV1/FVC % significantly decreased with increasing duration of diabetes. Conclusions: The present study shows that there is a statistically significant association between PFTs and type 2 DM in Indian patients. Pathologically it may be attributed to microangiopathic complications.
机译：背景：糖尿病（DM）的肺部并发症的特征很差。先前已有糖尿病患者报道肺活量降低。我们进行了一项研究，以检查2型DM中肺功能检查之间的关联。还要确定它们与体重指数（BMI），血糖控制和其他临床上明显的并发症（例如周围神经病）的相关性。方法：该研究在孟买BYL Nair医院的三级护理中进行，该糖尿病患者没有高血压，心血管疾病，原发性呼吸异常和无任何微血管病变的并发症。对他们进行了脉搏，血压，皮肤变化，BMI和各种生化检查的临床评估。记录了禁食和餐后血糖，血清胆固醇，血清甘油三酸酯，尿蛋白，心电图仪，X线胸片。通过肺活量测定法进行肺功能测试。寻找周围神经病变与肺功能检查（PFT）的关联。结果：200名患者中68％（136）患者的PFT正常，轻度阻塞10.0％（20），轻度限制10％（20）中度阻塞2％（4），中度限制4％（8）和混合6％ （12）被注意到。周围神经病患者的FEV1，FVC值在统计学上显着降低，而FEV1 / FVC％随着糖尿病持续时间的增加而显着降低。结论：本研究表明印度患者的PFT与2型DM之间存在统计学意义的关联。病理上可能归因于微血管病变并发症。

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