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首页> 外文期刊>International Journal of Research in Medical Sciences >To study prevalence of incipient iron deficiency in primary hypothyroidism
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To study prevalence of incipient iron deficiency in primary hypothyroidism

机译：研究原发性甲状腺功能减退症中初期铁缺乏症的患病率

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Background: Hypothyroidism, affects around 1% of general population. Anemia in association with hypothyroidism has been studied since 1881. Iron deficiency has multiple adverse effects on thyroid metabolism. It decreases circulating thyroid hormone concentration, blunts thyrotrophic response to TRH, decreases serum T3. Objective of current study was to find prevalence of iron deficiency in primary hypothyroid. Methods: In our study 70 patients were selected, out of which 50 were females and 20 were males, who were suffering from hypothyroidism. Iron deficiency in the study group was confirmed at baseline using multiple iron status indicators (serum ferritin, serum iron, TIBC & percentage Saturation). These patients were between age group 18-65 years. Results: In our study only 14 patients (20%) manifested with anemia (which was defined as Hb Conclusion: Iron deficiency was present in a significant portion of patients with primary hypothyroidism. It also concluded that frequency of iron deficiency (with or without anemia) was higher than iron deficiency anemia.
机译：背景：甲状腺功能减退症约占总人口的1％。自1881年以来就研究了与甲状腺功能减退有关的贫血。铁缺乏对甲状腺代谢有多种不利影响。它降低循环甲状腺激素浓度，钝化对TRH的甲状腺营养反应，降低血清T3。本研究的目的是发现原发性甲状腺功能减退症中铁缺乏症的患病率。方法：在我们的研究中，选择了患有甲状腺功能减退症的70例患者，其中女性50例，男性20例。在基线时使用多种铁状态指标（血清铁蛋白，血清铁，TIBC和饱和百分比）确认了研究组的铁缺乏。这些患者年龄在18-65岁之间。结果：在我们的研究中，只有14例患者（20％）表现为贫血（定义为Hb结论：在大部分原发性甲状腺功能减退症患者中存在铁缺乏症。还得出结论，铁缺乏症的频率（有或没有贫血） ）高于缺铁性贫血。

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