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首页> 外文期刊>International Journal of Reproduction, Contraception, Obstetrics and Gynecology >Risk of malignancy index 4 in preoperative evaluation of patients with ovarian tumours
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Risk of malignancy index 4 in preoperative evaluation of patients with ovarian tumours

机译：卵巢肿瘤患者术前评估中恶性指数4的风险

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Background: Ovarian tumors usually presents as adnexal masses which may be benign or malignant. Accurate and timely diagnosis of an adnexal mass is a challenge for the gynecologists. Currently clinical examination, ultrasonographic assessment and ovarian tumour markers (CA 125, beta hCG, AFP, LDH) are routinely done at our centre to evaluate patients with ovarian tumours. The study was designed to evaluate the ability of RMI 4 to discriminate benign ovarian tumor from malignant ovarian tumor in patients attending Department of Obstetrics and Gynaecology, S.M.S. Medical College, Jaipur. Methods: 200 patients diagnosed to have ovarian tumours were included in the study after obtaining written consent. Ultrasonographic characteristic, menopausal status and serum CA 125 levels were documented preoperatively. Risk of malignancy index 4 was calculated and correlated with histopathological diagnosis. Results: At a cut-off point of 450, RMI 4 had a sensitivity of 67.5% (95% CI: 50.87-81.43%), specificity of 98.75% (95.56-99.85%), positive likelyhood ratio of 54, negative likelyhood ratio of 0.33, a positive predictive value of 93.1%, negative predictive value of 92.4% and diagnostic accuracy of 92.5%. Conclusions: RMI 4 is a simple, cost effective, reliable scoring system that is easily applicable method in primary evaluation of patients with ovarian tumours with a sensitivity of 67.5% and specificity of 98.75%.
机译：背景：卵巢肿瘤通常表现为附件包块，可能是良性或恶性的。对妇科医师而言，准确，及时地诊断附件包块是一个挑战。目前，我们中心常规进行临床检查，超声检查和卵巢肿瘤标志物（CA 125，βhCG，AFP，LDH），以评估患有卵巢肿瘤的患者。该研究旨在评估RMI 4区分S.M.S.妇产科的患者卵巢良性肿瘤与恶性卵巢肿瘤的能力。斋浦尔医学院。方法：获得书面同意后，将200名被诊断患有卵巢肿瘤的患者纳入研究。术前记录了超声特征，绝经状态和血清CA 125水平。计算了恶性指数4的风险，并将其与组织病理学诊断相关。结果：在450的临界点，RMI 4的敏感性为67.5％（95％CI：50.87-81.43％），特异性为98.75％（95.56-99.85％），正似然比为54，负似然比预测值为0.33，阳性预测值为93.1％，阴性预测值为92.4％，诊断准确性为92.5％。结论：RMI 4是一种简单，经济高效，可靠的评分系统，可轻松应用于卵巢肿瘤患者的初步评估，灵敏度为67.5％，特异性为98.75％。

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