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首页> 外文期刊>International journal of rheumatology >Red Cell Distribution Width Is Positively Correlated with Atherosclerotic Cardiovascular Disease 10-Year Risk Score, Age, and CRP in Spondyloarthritis with Axial or Peripheral Disease
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Red Cell Distribution Width Is Positively Correlated with Atherosclerotic Cardiovascular Disease 10-Year Risk Score, Age, and CRP in Spondyloarthritis with Axial or Peripheral Disease

机译：红细胞分布宽度与伴有动脉粥样硬化性关节​​炎或轴索性周围疾病的动脉粥样硬化性心血管疾病的十年风险评分，年龄和CRP正相关

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Background. Red blood cell distribution width (RDW) is a routine hematologic parameter that is a predictor of cardiovascular disease (CVD) events and is independent of combined traditional risk factor scoring systems. The RDW has also been associated with rheumatic disease activity. Whether RDW is associated with traditional CVD risk factors or Atherosclerotic Cardiovascular Disease (ASCVD) 10-year CVD risk score in patients with seronegative spondyloarthritis with axial or peripheral disease has not been previously determined. Methods. We performed a retrospective, chart review study evaluating the relationship between RDW, albumin, hemoglobin, C-reactive protein (CRP), absolute lymphocyte count (ALC), and ASCVD scoring parameters [age, hypertension status, diabetes mellitus (DM) status, lipid profile, and smoking status] in a cohort of spondyloarthritis patients, taking into consideration their HLA-B27 status, race, and treatment status. Results. RDW was found to positively correlate with ASCVD 10-year score and age, and ASCVD score did not change over time after patients were treated for spondyloarthritis. Albumin was found to negatively correlate with ASCVD 10-year risk score. Both RDW and albumin correlated with CRP. ALC failed to correlate with ASCVD 10-year score but did show a tendency to be associated with CVD, CVD events, and cardiac conduction abnormalities. Conclusions. These data indicate that further study is warranted to evaluate RDW, albumin level, and ALC as potential predictors of CVD in the spondyloarthritis patient population.
机译：背景。红细胞分布宽度（RDW）是常规的血液学参数，可预测心血管疾病（CVD）事件，并且独立于传统的危险因素评分系统。 RDW也与风湿性疾病活动有关。 RDW是否与传统的CVD危险因素或动脉粥样硬化性颈椎炎伴轴向或周围性疾病的患者10年CVD危险评分相关。方法。我们进行了回顾性图表回顾研究，评估RDW，白蛋白，血红蛋白，C反应蛋白（CRP），绝对淋巴细胞计数（ALC）和ASCVD评分参数之间的关系[年龄，高血压状态，糖尿病（DM）状态，一组脊柱关节炎患者的血脂状况和吸烟状况]，要考虑他们的HLA-B27状况，种族和治疗状况。结果。发现RDW与ASCVD 10年评分和年龄呈正相关，并且在治疗了脊椎关节炎后ASCVD评分没有随时间变化。发现白蛋白与ASCVD 10年风险评分负相关。 RDW和白蛋白均与CRP相关。 ALC未能与ASCVD 10年评分相关，但确实显示出与CVD，CVD事件和心脏传导异常相关的趋势。结论。这些数据表明，有必要进行进一步的研究以评估RDW，白蛋白水平和ALC作为脊柱关节炎患者人群CVD的潜在预测因子。

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