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Temporal Trends in Chorioamnionitis by Maternal Race/Ethnicity and Gestational Age (1995–2010)

机译:按孕产妇种族/族裔和妊娠年龄分列的绒毛膜羊膜炎的时间趋势(1995-2010年)

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Objective. To characterize trends in chorioamnionitis (CAM) by maternal race/ethnicity and gestational age.Study Design. We examined trends in CAM from 1995–2010 among singleton births in all Kaiser Permanente Southern California hospitals (n=471,821). Data were extracted from Perinatal Service System and clinical utilization records. Gestational age- and race/ethnicity-specific biannual diagnosis rates were estimated using the Poisson regression after adjusting for potential confounding factors.Results. Overall diagnosis rates of CAM increased from 2.7% in 1995-1996 to 6.0% in 2009-2010 with a relative increase of 126% (95% confidence intervals [CI] 113%–149%). From 1995-1996 to 2009-2010, CAM increased among the Whites (1.8% to 4.3%,P-value for trend <.001), Blacks (2.2% to 3.7%,P-value for trend <.001), Hispanics (2.4% to 5.8%,P-value for trend <.001), and Asian/Pacific Islanders (3.6% to 9.0%,P-value for trend <.001). The adjusted relative percentage change in CAM from 1995-1996 to 2009-2010 was for Whites [preterm 21% (9%–78%), term 138% (108%–173%)], for Blacks [preterm 24% (−9%–81%), term 62% (30%–101%)], for Hispanics [preterm 31% (3%–66%), term 135% (114%–159%)], and for Asian/Pacific Islanders [preterm 44% (9%–127%), term 145% (109%–188%)].Conclusion. The findings suggest that CAM diagnosis rate has increased for all race/ethnic groups. This increase is primarily due to increased diagnosis at term gestation.
机译:目的。通过孕产妇种族/族裔和胎龄来表征绒毛膜羊膜炎(CAM)的趋势研究设计。我们研究了1995-2010年间南加州所有Kaiser Permanente医院(n = 471,821)单胎出生的CAM趋势。从围产期服务系统和临床使用记录中提取数据。校正潜在的混杂因素后,使用Poisson回归评估了特定于妊娠年龄和种族/种族的双年度诊断率。 CAM的总体诊断率从1995-1996年的2.7%提高到2009-2010年的6.0%,相对增加了126%(95%置信区间[CI] 113%–149%)。从1995-1996年到2009-2010年,白人中的CAM增长(1.8%至4.3%,趋势的P值<.001),黑人(2.2%至3.7%,趋势的P值<.001),西班牙裔(2.4%至5.8%,趋势的P值<.001)和亚洲/太平洋岛民(3.6%至9.0%,趋势的P值<.001)。从1995-1996年到2009-2010年的CAM相对调整百分比变化是白人[早产21%(9%–78%),任期138%(108%–173%)],黑人[早产24%(- 9%–81%),学期62%(30%–101%)],西班牙裔[学龄前31%(3%–66%),学期135%(114%–159%)]和亚太地区岛民[早产44%(9%–127%),学期145%(109%–188%)]。结论。研究结果表明,所有种族/族裔群体的CAM诊断率都有所提高。这种增加主要是由于足月妊娠的诊断增加。

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