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首页> 外文期刊>International journal of rheumatology >Churg-Strauss Syndrome following PTU Treatment
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Churg-Strauss Syndrome following PTU Treatment

机译：PTU治疗后的Churg-Strauss综合征

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Propylthiouracil (PTU) is a frequently prescribed drug in the treatment of hyperthyroidism. The use of PTU is, however, accompanied by numerous potentially serious side effects including vasculitis. PTU-related vasculitides can present as haematuria, pulmonary haemorrhage, or cutaneous lesion together with aspecific symptoms such as fever, myalgia, arthralgia, and fatigue. Cerebral involvement is seldom observed. We present a 49-year-old female with Graves' disease and asthma, who developed paresis of the proximal extremities, eosinophilia, pulmonary, and cutaneous lesions following treatment with PTU. A cerebral vasculitis consistent with Churg-Strauss syndrome (CSS) was suspected. Although cerebral involvement is seldom observed with PTU treatment, cerebral vasculitis should be considered in patients developing CNS symptoms.
机译：丙硫氧嘧啶（PTU）是治疗甲状腺功能亢进症的常用处方药。但是，使用PTU会伴随许多潜在的严重副作用，包括血管炎。与PTU相关的血管炎可表现为血尿，肺出血或皮肤病变以及非特异性症状，例如发烧，肌痛，关节痛和疲劳。很少有大脑受累。我们介绍了一名49岁的女性，患有Graves病和哮喘，在接受PTU治疗后出现近端肢体轻瘫，嗜酸性粒细胞增多，肺部和皮肤病变。怀疑患有Churg-Strauss综合征（CSS）的脑血管炎。尽管用PTU治疗很少观察到脑部受累，但是在出现CNS症状的患者中应考虑脑血管炎。

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